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Glucocorticoid Signaling

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Attention for Chapter 2: Molecular Biology of Glucocorticoid Signaling.
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23 Mendeley
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Chapter title
Molecular Biology of Glucocorticoid Signaling.
Chapter number 2
Book title
Glucocorticoid Signaling
Published in
Advances in experimental medicine and biology, January 2015
DOI 10.1007/978-1-4939-2895-8_2
Pubmed ID
Book ISBNs
978-1-4939-2894-1, 978-1-4939-2895-8
Authors

Arango-Lievano, Margarita, Lambert, W Marcus, Jeanneteau, Freddy, Margarita Arango-Lievano, W. Marcus Lambert, Freddy Jeanneteau, Lambert, W. Marcus

Abstract

Well-defined as signaling hormones for the programming of cell type-specific and context-dependent gene expression signatures, glucocorticoids control experience-driven allostasis. One unifying model is that glucocorticoids help maintaining the integrity and plasticity of cellular networks in changing environments through the mobilization of cellular energy stores, profiling of gene expression, and changes in the electrical and morphological properties of cells. The nucleus is their primary site of action, yet recent discoveries point to additional gene transcription-independent functions at the plasma membrane of neuronal synapses. Glucocorticoids are secreted factors that reflect intrinsically the changes coming from the external world, temporally and regionally, during development and adulthood. In this review, we will enumerate the properties and signaling attributes of glucocorticoids and their receptors that characterize them as allostatic modulators. The molecular mechanisms used to support their role at the synapse will be highlighted.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 30%
Student > Bachelor 3 13%
Student > Master 3 13%
Professor 2 9%
Student > Doctoral Student 2 9%
Other 0 0%
Unknown 6 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 17%
Medicine and Dentistry 3 13%
Biochemistry, Genetics and Molecular Biology 2 9%
Psychology 2 9%
Nursing and Health Professions 1 4%
Other 3 13%
Unknown 8 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2015.
All research outputs
#15,340,815
of 22,818,766 outputs
Outputs from Advances in experimental medicine and biology
#2,502
of 4,950 outputs
Outputs of similar age
#208,994
of 353,109 outputs
Outputs of similar age from Advances in experimental medicine and biology
#119
of 272 outputs
Altmetric has tracked 22,818,766 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,950 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,109 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 272 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.