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PEGylated Protein Drugs: Basic Science and Clinical Applications

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Cover of 'PEGylated Protein Drugs: Basic Science and Clinical Applications'

Table of Contents

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    Book Overview
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    Chapter 1 Preface PEGylated protein conjugates: A new class of therapeutics for the 21st century
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    Chapter 2 Protein PEGylation, basic science and biological applications
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    Chapter 3 Reactive PEGs for protein conjugation
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    Chapter 4 Rebridging disulphides: site-specific PEGylation by sequential bis-alkylation
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    Chapter 5 Enzymatic techniques for PEGylation of biopharmaceuticals
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    Chapter 6 The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
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    Chapter 7 Protein conjugates purification and characterization
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    Chapter 8 PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
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    Chapter 9 The occurrence, induction, specificity and potential effect of antibodies against poly(ethylene glycol)
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    Chapter 10 Pegfilgrastim — designing an improved form of rmetHuG-CSF
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    Chapter 11 PEGylation of human growth hormone: strategies and properties
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    Chapter 12 PEGylated α interferons: two different strategies to achieve increased efficacy
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    Chapter 13 Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout
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    Chapter 14 Certolizumab pegol: a PEGylated anti-tumour necrosis factor alpha biological agent
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    Chapter 15 PEG: a useful technology in anticancer therapy
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    Chapter 16 Regulatory strategy and approval processes considered for PEG-drug conjugates and other nanomedicines
Attention for Chapter 8: PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
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Chapter title
PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
Chapter number 8
Book title
PEGylated Protein Drugs: Basic Science and Clinical Applications
Published by
Birkhäuser Basel, January 2009
DOI 10.1007/978-3-7643-8679-5_8
Book ISBNs
978-3-76-438678-8, 978-3-76-438679-5
Authors

Rob Webster, Victoria Elliott, B. Kevin Park, Donald Walker, Mark Hankin, Philip Taupin, Webster, Rob, Elliott, Victoria, Park, B. Kevin, Walker, Donald, Hankin, Mark, Taupin, Philip

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X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 181 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Russia 2 1%
Germany 2 1%
United States 1 <1%
Switzerland 1 <1%
Unknown 175 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 46 25%
Researcher 31 17%
Student > Master 22 12%
Student > Bachelor 13 7%
Student > Doctoral Student 9 5%
Other 23 13%
Unknown 37 20%
Readers by discipline Count As %
Chemistry 34 19%
Medicine and Dentistry 17 9%
Pharmacology, Toxicology and Pharmaceutical Science 16 9%
Materials Science 16 9%
Engineering 14 8%
Other 41 23%
Unknown 43 24%

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