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Phosphodiesterases as Drug Targets

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Cover of 'Phosphodiesterases as Drug Targets'

Table of Contents

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    Book Overview
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    Chapter 1 Phosphodiesterase Inhibitors: History of Pharmacology
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    Chapter 2 Phosphodiesterase Inhibitors: Factors That Influence Potency, Selectivity, and Action
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    Chapter 3 Pharmacology, clinical efficacy, and tolerability of phosphodiesterase-4 inhibitors: impact of human pharmacokinetics.
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    Chapter 4 Structural Insight into the Substrate Specificity of Phosphodiesterases
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    Chapter 5 A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity
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    Chapter 6 The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
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    Chapter 7 Small Molecule Allosteric Modulators of Phosphodiesterase 4
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    Chapter 8 Regulation of Endothelial Barrier Function by Cyclic Nucleotides: The Role of Phosphodiesterases
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    Chapter 9 Phosphodiesterases as Targets for Intermittent Claudication
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    Chapter 10 Phosphodiesterase Inhibition in Heart Failure
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    Chapter 11 Phosphodiesterases: Emerging Therapeutic Targets for Neonatal Pulmonary Hypertension
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    Chapter 12 Role of Phosphodiesterases in Adult-Onset Pulmonary Arterial Hypertension
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    Chapter 13 Treatment of Erectile Dysfunction and Lower Urinary Tract Symptoms by Phosphodiesterase Inhibitors
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    Chapter 14 Evaluation of the Therapeutic Utility of Phosphodiesterase 5A Inhibition in the mdx Mouse Model of Duchenne Muscular Dystrophy
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    Chapter 15 Phosphodiesterases as Targets for Modulating T-Cell Responses
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    Chapter 16 Cyclic Nucleotides and Phosphodiesterases in Monocytic Differentiation
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    Chapter 17 Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases
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    Chapter 18 Harnessing the Clinical Efficacy of Phosphodiesterase 4 Inhibitors in Inflammatory Lung Diseases: Dual-Selective Phosphodiesterase Inhibitors and Novel Combination Therapies
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    Chapter 19 Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders
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    Chapter 20 Therapeutic Potential of Phosphodiesterase Inhibitors in Parasitic Diseases
Attention for Chapter 19: Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders
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Chapter title
Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders
Chapter number 19
Book title
Phosphodiesterases as Drug Targets
Published in
Handbook of experimental pharmacology, January 2011
DOI 10.1007/978-3-642-17969-3_19
Pubmed ID
Book ISBNs
978-3-64-217968-6, 978-3-64-217969-3
Authors

Ying Xu, Han-Ting Zhang, James M. O’Donnell, Xu, Ying, Zhang, Han-Ting, O’Donnell, James M.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Netherlands 1 2%
Unknown 61 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 22%
Student > Ph. D. Student 12 19%
Student > Bachelor 7 11%
Professor > Associate Professor 7 11%
Student > Master 4 6%
Other 7 11%
Unknown 12 19%
Readers by discipline Count As %
Neuroscience 14 22%
Agricultural and Biological Sciences 8 13%
Medicine and Dentistry 7 11%
Psychology 5 8%
Chemistry 4 6%
Other 8 13%
Unknown 17 27%