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Phosphodiesterases as Drug Targets

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Cover of 'Phosphodiesterases as Drug Targets'

Table of Contents

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    Book Overview
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    Chapter 1 Phosphodiesterase Inhibitors: History of Pharmacology
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    Chapter 2 Phosphodiesterase Inhibitors: Factors That Influence Potency, Selectivity, and Action
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    Chapter 3 Pharmacology, clinical efficacy, and tolerability of phosphodiesterase-4 inhibitors: impact of human pharmacokinetics.
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    Chapter 4 Structural Insight into the Substrate Specificity of Phosphodiesterases
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    Chapter 5 A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity
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    Chapter 6 The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
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    Chapter 7 Small Molecule Allosteric Modulators of Phosphodiesterase 4
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    Chapter 8 Regulation of Endothelial Barrier Function by Cyclic Nucleotides: The Role of Phosphodiesterases
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    Chapter 9 Phosphodiesterases as Targets for Intermittent Claudication
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    Chapter 10 Phosphodiesterase Inhibition in Heart Failure
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    Chapter 11 Phosphodiesterases: Emerging Therapeutic Targets for Neonatal Pulmonary Hypertension
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    Chapter 12 Role of Phosphodiesterases in Adult-Onset Pulmonary Arterial Hypertension
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    Chapter 13 Treatment of Erectile Dysfunction and Lower Urinary Tract Symptoms by Phosphodiesterase Inhibitors
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    Chapter 14 Evaluation of the Therapeutic Utility of Phosphodiesterase 5A Inhibition in the mdx Mouse Model of Duchenne Muscular Dystrophy
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    Chapter 15 Phosphodiesterases as Targets for Modulating T-Cell Responses
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    Chapter 16 Cyclic Nucleotides and Phosphodiesterases in Monocytic Differentiation
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    Chapter 17 Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases
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    Chapter 18 Harnessing the Clinical Efficacy of Phosphodiesterase 4 Inhibitors in Inflammatory Lung Diseases: Dual-Selective Phosphodiesterase Inhibitors and Novel Combination Therapies
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    Chapter 19 Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders
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    Chapter 20 Therapeutic Potential of Phosphodiesterase Inhibitors in Parasitic Diseases
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Chapter title
Phosphodiesterase Inhibitors: History of Pharmacology
Chapter number 1
Book title
Phosphodiesterases as Drug Targets
Published in
Handbook of experimental pharmacology, January 2011
DOI 10.1007/978-3-642-17969-3_1
Pubmed ID
Book ISBNs
978-3-64-217968-6, 978-3-64-217969-3
Authors

Christian Schudt, Armin Hatzelmann, Rolf Beume, Hermann Tenor, Schudt, Christian, Hatzelmann, Armin, Beume, Rolf, Tenor, Hermann

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Norway 1 1%
Unknown 74 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 16%
Student > Bachelor 10 13%
Student > Ph. D. Student 8 11%
Student > Master 8 11%
Professor 6 8%
Other 15 20%
Unknown 17 22%
Readers by discipline Count As %
Medicine and Dentistry 25 33%
Agricultural and Biological Sciences 8 11%
Chemistry 5 7%
Nursing and Health Professions 3 4%
Immunology and Microbiology 2 3%
Other 12 16%
Unknown 21 28%