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Phosphodiesterases as Drug Targets

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Cover of 'Phosphodiesterases as Drug Targets'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Phosphodiesterase Inhibitors: History of Pharmacology
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    Chapter 2 Phosphodiesterase Inhibitors: Factors That Influence Potency, Selectivity, and Action
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    Chapter 3 Pharmacology, clinical efficacy, and tolerability of phosphodiesterase-4 inhibitors: impact of human pharmacokinetics.
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    Chapter 4 Structural Insight into the Substrate Specificity of Phosphodiesterases
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    Chapter 5 A Fission Yeast-Based Platform for Phosphodiesterase Inhibitor HTSs and Analyses of Phosphodiesterase Activity
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    Chapter 6 The GAF-Tandem Domain of Phosphodiesterase 5 as a Potential Drug Target
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    Chapter 7 Small Molecule Allosteric Modulators of Phosphodiesterase 4
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    Chapter 8 Regulation of Endothelial Barrier Function by Cyclic Nucleotides: The Role of Phosphodiesterases
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    Chapter 9 Phosphodiesterases as Targets for Intermittent Claudication
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    Chapter 10 Phosphodiesterase Inhibition in Heart Failure
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    Chapter 11 Phosphodiesterases: Emerging Therapeutic Targets for Neonatal Pulmonary Hypertension
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    Chapter 12 Role of Phosphodiesterases in Adult-Onset Pulmonary Arterial Hypertension
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    Chapter 13 Treatment of Erectile Dysfunction and Lower Urinary Tract Symptoms by Phosphodiesterase Inhibitors
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    Chapter 14 Evaluation of the Therapeutic Utility of Phosphodiesterase 5A Inhibition in the mdx Mouse Model of Duchenne Muscular Dystrophy
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    Chapter 15 Phosphodiesterases as Targets for Modulating T-Cell Responses
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    Chapter 16 Cyclic Nucleotides and Phosphodiesterases in Monocytic Differentiation
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    Chapter 17 Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases
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    Chapter 18 Harnessing the Clinical Efficacy of Phosphodiesterase 4 Inhibitors in Inflammatory Lung Diseases: Dual-Selective Phosphodiesterase Inhibitors and Novel Combination Therapies
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    Chapter 19 Phosphodiesterases in the Central Nervous System: Implications in Mood and Cognitive Disorders
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    Chapter 20 Therapeutic Potential of Phosphodiesterase Inhibitors in Parasitic Diseases
Attention for Chapter 17: Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases
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Chapter title
Phosphodiesterase Inhibitors in the Treatment of Inflammatory Diseases
Chapter number 17
Book title
Phosphodiesterases as Drug Targets
Published in
Handbook of experimental pharmacology, January 2011
DOI 10.1007/978-3-642-17969-3_17
Pubmed ID
Book ISBNs
978-3-64-217968-6, 978-3-64-217969-3
Authors

C. P. Page, D. Spina, Page, C. P., Spina, D.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Unknown 69 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 17%
Student > Ph. D. Student 11 16%
Student > Master 7 10%
Student > Bachelor 6 9%
Student > Postgraduate 5 7%
Other 13 19%
Unknown 16 23%
Readers by discipline Count As %
Medicine and Dentistry 21 30%
Biochemistry, Genetics and Molecular Biology 10 14%
Agricultural and Biological Sciences 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 6 9%
Immunology and Microbiology 2 3%
Other 4 6%
Unknown 21 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2018.
All research outputs
#18,604,390
of 23,045,021 outputs
Outputs from Handbook of experimental pharmacology
#505
of 647 outputs
Outputs of similar age
#161,467
of 181,816 outputs
Outputs of similar age from Handbook of experimental pharmacology
#19
of 22 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 647 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 181,816 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.