Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
Springer International Publishing
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Timeline
Mendeley readers
| Chapter title |
H 2 S Is a Promoter of Angiogenesis: Identification of H 2 S “Receptors” and Its Molecular Switches in Vascular Endothelial Cells
|
|---|---|
| Chapter number | 6 |
| Book title |
Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
|
| Published in |
Handbook of experimental pharmacology, January 2015
|
| DOI | 10.1007/978-3-319-18144-8_6 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-918143-1, 978-3-31-918144-8
|
| Authors |
Bei-Bei Tao, Wen-Jie Cai, Yi-Chun Zhu, Tao, Bei-Bei, Cai, Wen-Jie, Zhu, Yi-Chun |
| Abstract |
Angiogenesis is a physiological process in organ development and also a compensatory response in ischemia. When ischemia occurs, oxygen sensors in vascular endothelial cells sense the decrease in oxygen, thus activating downstream signaling pathways to promote the proliferation, migration, and tube formation of the endothelial cells. The new vasculatures are formed by sprouting from preexisting vessels, in order to maintain oxygen homeostasis in ischemic tissues (Folkman and Shing 1992). Collateral circulation is sometimes established under chronic ischemic conditions such as chronic myocardial ischemia (Banai et al. 1994). However, naturally occurring angiogenesis is usually not sufficient to compensate for ischemia in ischemic tissues. Proangiogenic drugs may be useful to promote angiogenesis in these diseases. |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 2 | 14% |
| Student > Ph. D. Student | 2 | 14% |
| Student > Master | 2 | 14% |
| Student > Bachelor | 1 | 7% |
| Unspecified | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 5 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 3 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 14% |
| Unspecified | 1 | 7% |
| Neuroscience | 1 | 7% |
| Biochemistry, Genetics and Molecular Biology | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 6 | 43% |