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PEGylated Protein Drugs: Basic Science and Clinical Applications

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Cover of 'PEGylated Protein Drugs: Basic Science and Clinical Applications'

Table of Contents

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    Book Overview
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    Chapter 1 Preface PEGylated protein conjugates: A new class of therapeutics for the 21st century
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    Chapter 2 Protein PEGylation, basic science and biological applications
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    Chapter 3 Reactive PEGs for protein conjugation
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    Chapter 4 Rebridging disulphides: site-specific PEGylation by sequential bis-alkylation
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    Chapter 5 Enzymatic techniques for PEGylation of biopharmaceuticals
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    Chapter 6 The site-specific TGase-mediated PEGylation of proteins occurs at flexible sites
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    Chapter 7 Protein conjugates purification and characterization
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    Chapter 8 PEG and PEG conjugates toxicity: towards an understanding of the toxicity of PEG and its relevance to PEGylated biologicals
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    Chapter 9 The occurrence, induction, specificity and potential effect of antibodies against poly(ethylene glycol)
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    Chapter 10 Pegfilgrastim — designing an improved form of rmetHuG-CSF
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    Chapter 11 PEGylation of human growth hormone: strategies and properties
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    Chapter 12 PEGylated α interferons: two different strategies to achieve increased efficacy
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    Chapter 13 Development of PEGylated mammalian urate oxidase as a therapy for patients with refractory gout
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    Chapter 14 Certolizumab pegol: a PEGylated anti-tumour necrosis factor alpha biological agent
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    Chapter 15 PEG: a useful technology in anticancer therapy
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    Chapter 16 Regulatory strategy and approval processes considered for PEG-drug conjugates and other nanomedicines
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Chapter title
Protein PEGylation, basic science and biological applications
Chapter number 2
Book title
PEGylated Protein Drugs: Basic Science and Clinical Applications
Published by
Birkhäuser Basel, January 2009
DOI 10.1007/978-3-7643-8679-5_2
Book ISBNs
978-3-76-438678-8, 978-3-76-438679-5
Authors

Francesco M. Veronese, Anna Mero, Gianfranco Pasut

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 3%
France 1 3%
Unknown 37 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 21%
Researcher 6 15%
Student > Master 5 13%
Student > Doctoral Student 3 8%
Professor > Associate Professor 2 5%
Other 4 10%
Unknown 11 28%
Readers by discipline Count As %
Chemistry 7 18%
Biochemistry, Genetics and Molecular Biology 5 13%
Pharmacology, Toxicology and Pharmaceutical Science 4 10%
Agricultural and Biological Sciences 3 8%
Chemical Engineering 2 5%
Other 5 13%
Unknown 13 33%