G-Quadruplex DNA

Chapter 1 G-Quadruplexes: From Guanine Gels to Chemotherapeutics

Chapter 2 Molecular Modeling and Simulation of G-Quadruplexes and Quadruplex-Ligand Complexes

Chapter 3 Computational Approaches to the Detection and Analysis of Sequences with Intramolecular G-Quadruplex Forming Potential

Chapter 4 Preparation of G-Quartet Structures and Detection by Native Gel Electrophoresis

Chapter 5 Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay.

Chapter 6 Real-Time Observation of G-Quadruplex Dynamics Using Single-Molecule FRET Microscopy

Chapter 7 Sedimentation velocity ultracentrifugation analysis for hydrodynamic characterization of G-quadruplex structures.

Chapter 8 2-aminopurine as a probe for quadruplex loop structures.

Chapter 9 Assessing DNA Structures with 125 I Radioprobing

Chapter 10 Monitoring the Temperature Unfolding of G-Quadruplexes by UV and Circular Dichroism Spectroscopies and Calorimetry Techniques

Chapter 11 Probing Telomeric G-Quadruplex DNA Structures in Cells with In Vitro Generated Single-Chain Antibody Fragments

Chapter 12 Detection of G-Quadruplexes in Cells and Investigation of G-Quadruplex Structure of d(T2AG3)4 in K+ Solution by a Carbazole Derivative: BMVC

Chapter 13 Isolation of G-Quadruplex DNA Using NMM-Sepharose Affinity Chromatography

Chapter 14 Quantifying Interactions Between G-Quadruplex DNA and Transition-Metal Complexes

Chapter 15 G4-FID: A Fluorescent DNA Probe Displacement Assay for Rapid Evaluation of Quadruplex Ligands