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Pharmacokinetics

Overview of attention for book
Cover of 'Pharmacokinetics'

Table of Contents

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    Book Overview
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    Chapter 1 Sidney Riegelman — The Wisconsin Years
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    Chapter 2 Sidney Riegelman — Friend and Colleague
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    Chapter 3 Sidney Riegelman — The Educator
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    Chapter 4 Sidney Riegelman — The Scientist
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    Chapter 5 Sidney Riegelman — His Contributions to Public Policy in Pharmacy and The Pharmaceutical Sciences
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    Chapter 6 Sidney Riegelman — Contributions at the Clinical Interface
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    Chapter 7 Personal Experiences in the Early Days of Biopharmacy and Pharmacokinetics
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    Chapter 8 Modern Pharmaceutical Dosage Forms
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    Chapter 9 Specificity of Esterases and Effect of Structure of Prodrug Esters of Acylated Acetaminophen on Hydrolytic Reactivity
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    Chapter 10 Transdermal Absorption: A Unique Opportunity for Drug Delivery
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    Chapter 11 Pharmacokinetics and Pharmaceutical Technology
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    Chapter 12 Bioavailability and Pharmacokinetics in Drug Development
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    Chapter 13 Clearance — Models, Validation and Implications
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    Chapter 14 Estimation of an Effective Half-Life
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    Chapter 15 Pharmacokinetic Aspects of Nonlinear Drug-Protein Binding
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    Chapter 16 Unusual Pharmacokinetics
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    Chapter 17 Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity
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    Chapter 18 Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man
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    Chapter 19 Problems in Correlating In Vitro and In Vivo Studies of Drug Metabolism
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    Chapter 20 Integral Procedures in Pharmacokinetics and their Application to the Parameter Determination of Appearing Metabolites
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    Chapter 21 Pharmacokinetics at the Interface Between Pharmacology and Physiology
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    Chapter 22 Methods for Drug Dosage Individualization: Past, Present and Future
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    Chapter 23 Treatment of Depression — Pharmacokinetic and Pharmacogenetic Considerations
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    Chapter 24 Kinetics of Drug Action
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    Chapter 25 Cancer Drug Delivery Systems: Macromolecular Prodrugs of Mitomycin C
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    Chapter 26 Organ Variation in Tissue to Plasma Partition Coefficients of Adriamycin, Daunomycin and Actinomycin-D: Correlation to Tissue DNA Concentrations
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    Chapter 27 Clinical Pharmacokinetics in the Therapeutic Management of Cancer Patients with Methotrexate and Adriamycin
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    Chapter 28 The Immunopharmacokinetics of Prednisone/Prednisolone
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    Chapter 29 The Interpretation of In Vivo Mean Dissolution Time Data
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    Chapter 30 Application of Statistical Moment Analysis to the Evaluation of Controlled Release Formulations
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    Chapter 31 Concept of Time-Averaged Total Clearance and Mean Residence Time in Michaelis-Menten Elimination Systems
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    Chapter 32 A General Method of Optimizing Individual Drug Dosage
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    Chapter 33 Estimation of Population Pharmacokinetic Parameters with the Computer System Nonmem: Patients Treated with Lidocaine and Mexiletine
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    Chapter 34 Considerations of Linear Regression with Errors in both Variables as Applied to Clinical Pharmacokinetics
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    Chapter 35 Intestinal Drug Metabolism — Presystemic and Systemic Mechanisms and Implications
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    Chapter 36 Pharmacokinetics of Aspirin: Total and Presystemic Clearance by Rats and Hydrolysis in Blood of Rats and Humans
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    Chapter 37 Do Plasma Concentrations of Acetaminophen and its Conjugated Metabolites Reflect Concentrations in Various Tissues?
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    Chapter 38 Interspecies Variations in Pharmacokinetics: A Perspective
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    Chapter 39 Nonrenal Elimination, Extensive Renal Tubular Reabsorption and Secretion of Creatinine in Humans and Animals
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    Chapter 40 Phenobarbital Pharmacokinetics with Particular Emphasis on the Treatment of Overdosed Patients
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    Chapter 41 Renal Elimination in Alcoholic Cirrhosis
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    Chapter 42 Altered Disposition of Naproxen by Cirrhotic and by Elderly Individuals
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    Chapter 43 Drug-Drug Interactions: Protean Manifestations
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    Chapter 44 Kinetics and Antiarrhythmic Effect of Dihydroquinidine
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    Chapter 45 Quinidine-N-Oxide: Structure and Pharmacokinetics of a New Quinidine Metabolite
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    Chapter 46 Phenobarbital Induction of Quinidine Plasma Protein Binding in Dogs and its Effect on Quinidine Disposition
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    Chapter 47 Covalent Binding of Quinidine
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    Chapter 48 The Use of the Portacaval Transposition Technique to Study Gastrointestinal and Hepatic Metabolism of Propranolol in Dogs
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    Chapter 49 Stereoselective Disposition and Glucuronidation of Propranolol in Man
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    Chapter 50 Effect of Renal and Hepatic Insufficiency on the Pharmacokinetics of Betaxolol, A New Adrenergic ß-Blocker
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    Chapter 51 A Selective HPLC Assay for Simultaneous Quantitation of Fourteen Methylxanthines and Methyluric Acids in Urine
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    Chapter 52 A Composite View of Theophylline Elimination in Man
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    Chapter 53 The Influence of Food on the Bioavailability of a Sustained Release Theophylline Formulation
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    Chapter 54 Pharmacokinetics of the Vasodilators Hydralazine and Endralazine
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    Chapter 55 Formation of Mono- and Dinitrate Metabolites of Nitroglycerin Following Incubation with Human Blood
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    Chapter 56 A Pharmacodynamic Model for Thiazinamium in Asthmatic Patients
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    Chapter 57 Protein Binding Estimates in the Presence of Volume Shifts During Equilibrium Dialysis
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    Chapter 58 Opiate Pharmacokinetics: In Vivo Receptor Binding and Pharmacological Effects
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    Chapter 59 Cefoperazone Pharmacokinetics in Healthy Chinese Volunteers
Attention for Chapter 17: Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity
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Chapter title
Assessment and Prediction of In Vivo Oxidative Drug Metabolizing Activity
Chapter number 17
Book title
Pharmacokinetics
Published by
Springer, Boston, MA, January 1984
DOI 10.1007/978-1-4613-2799-8_17
Book ISBNs
978-1-4612-9725-3, 978-1-4613-2799-8
Authors

Douwe D. Breimer, Nico P. E. Vermeulen, Meindert Danhof, Michiel W. E. Teunissen, Rolf P. Joeres, Martin van der Graaff, Breimer, Douwe D., Vermeulen, Nico P. E., Danhof, Meindert, Teunissen, Michiel W. E., Joeres, Rolf P., van der Graaff, Martin

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Mendeley readers

The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 1 100%
Readers by discipline Count As %
Unknown 1 100%

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