Vitamin D Analogs in Cancer Prevention and Therapy

Chapter 1 Evolution and function of vitamin D.

Chapter 2 Current Understanding of the Function of the Nuclear Vitamin D Receptor in Response to Its Natural and Synthetic Ligands

Chapter 3 Approaches to Evaluating the Association of Vitamin D Receptor Gene Polymorphisms with Breast Cancer Risk

Chapter 4 Ligand Structure—Function Relationships in the Vitamin D Endocrine System from the Perspective of Drug Development (Including Cancer Treatment)

Chapter 5 Antiproliferative signalling by 1,25(OH)2D3 in prostate and breast cancer is suppressed by a mechanism involving histone deacetylation.

Chapter 6 Mechanisms Implicated in the Growth Regulatory Effects of Vitamin D Compounds in Breast Cancer Cells

Chapter 7 Squamous Cell Carcinomas Fail to Respond to the Prodifferentiating Actions of 1,25(OH) 2 D 3 : Why?

Chapter 8 A Novel Vitamin D-Regulated Immediate-Early Gene, IEX-1, Alters Cellular Growth and Apoptosis

Chapter 9 Extrarenal Sites of Calcitriol Synthesis:The Particular Role of the Skin

Chapter 10 Cultured Rat Growth Plate Chondrocytes Express Low Levels of 1α-Hydroxylase

Chapter 11 Gene amplification and splice variants of 25-hydroxyvitamin D3 1,alpha-hydroxylase (CYP27B1) in glioblastoma multiforme--a possible role in tumor progression?

Chapter 12 Regulation of the 25-Hydroxyvitamin D-1α-Hydroxylase Gene and Its Splice Variant

Chapter 13 Combination of Vitamin D Metabolites with Selective Inhibitors of Vitamin D Metabolism

Chapter 14 Importance Of Cytochrome P450-Mediated Metabolism in the Mechanism of Action of Vitamin D Analogs

Chapter 15 The Role of Vitamin D in Prostate Cancer

Chapter 16 Vitamin D Autocrine System and Prostate Cancer

Chapter 17 Analysis of the Vitamin D System in Cervical Carcinomas, Breast Cancer and Ovarian Cancer

Chapter 18 Short-Chain Fatty Acids and Colon Cancer Cells: The Vitamin D Receptor—Butyrate Connection

Chapter 19 Analysis of the Vitamin D system in Cutaneous Malignancies

Chapter 20 Evaluation of vitamin D analogs as therapeutic agents for prostate cancer.

Chapter 21 Design, Synthesis, and Biological Studies of the A-Ring-Modified 1,25-Dihydroxyvitamin D 3 Analogs

Chapter 22 Induction of Apoptosis by Vitamin D Metabolites and Analogs in a Glioma Cell Line

Chapter 23 Vitamin D Analogs and Breast Cancer

Chapter 24 A Low-Calcemic Vitamin D Analog (Ro 25-4020) Inhibits the Growth of LNCaP Human Prostate Cancer Cells with Increased Potency by Producing an Active 24-Oxo Metabolite (Ro 29-9970)

Chapter 25 Prospects for Vitamin D receptor Modulators as Candidate Drugs for Cancer and (Auto)immune Diseases

Chapter 26 The Role of Reactive Oxygen Species in the Anticancer Activity of Vitamin D

Chapter 27 Ecologic Studies of Solar UV-B Radiation and Cancer Mortality Rates

Chapter 28 Phytoestrogens and 17β-Estradiol Influence Vitamin D Metabolism and Receptor Expression—Relevance for Colon Cancer Prevention

Chapter 29 Efficacy and Mechanism of Action of 1α-hydroxy-24-ethyl-Cholecalciferol (1α[OH]D5) in Breast Cancer Prevention and Therapy

Chapter 30 Regulation of Extrarenal Vitamin D Metabolism as a Tool for Colon and Prostate Cancer Prevention

Chapter 31 Modulation of X-ray-Induced Apoptosis in Human Keratinocytes (HaCaT) by 1,25-Dihydroxyvitamin D 3