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Mendeley readers
Chapter title |
Detection of APOBEC3 Proteins and Catalytic Activity in Urothelial Carcinoma
|
---|---|
Chapter number | 8 |
Book title |
Urothelial Carcinoma
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7234-0_8 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7233-3, 978-1-4939-7234-0
|
Authors |
Ananda Ayyappan Jaguva Vasudevan, Wolfgang Goering, Dieter Häussinger, Carsten Münk, Jaguva Vasudevan, Ananda Ayyappan, Goering, Wolfgang, Häussinger, Dieter, Münk, Carsten |
Abstract |
Members of the APOBEC3 (A3) family of enzymes were shown to act in an oncogenic manner in several cancer types. Immunodetection of APOBEC3A (A3A), APOBEC3B (A3B), and APOBEC3G (A3G) proteins is particularly challenging due to the large sequence homology of these proteins and limited availability of antibodies. Here we combine independent immunoblotting with an in vitro activity assay technique, to detect and categorize specific A3s expressed in urothelial bladder cancer and other cancer cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 4 | 36% |
Student > Bachelor | 2 | 18% |
Researcher | 1 | 9% |
Student > Doctoral Student | 1 | 9% |
Unknown | 3 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 5 | 45% |
Agricultural and Biological Sciences | 2 | 18% |
Medicine and Dentistry | 1 | 9% |
Unknown | 3 | 27% |