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| Chapter title |
Conclusions
|
|---|---|
| Chapter number | 5 |
| Book title |
Disordered Vertebral and Rib Morphology in Pudgy Mice
|
| Published in |
Advances in anatomy embryology and cell biology, January 2016
|
| DOI | 10.1007/978-3-319-43151-2_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-943149-9, 978-3-31-943151-2
|
| Authors |
Frederic Shapiro |
| Abstract |
The abnormal findings in the pudgy mouse are remarkably similar to those in the severe case of human congenital scoliosis such as seen in the spondylocostal dysplasias. The pudgy mouse is an excellent model to study: (i) how gene mutations translate into three-dimensional structural abnormalities and (ii) which other factors contribute to the final deformities. |