Chapter title |
Biomaterials Made from Coiled-Coil Peptides
|
---|---|
Chapter number | 17 |
Book title |
Fibrous Proteins: Structures and Mechanisms
|
Published in |
Sub cellular biochemistry, January 2017
|
DOI | 10.1007/978-3-319-49674-0_17 |
Pubmed ID | |
Book ISBNs |
978-3-31-949672-6, 978-3-31-949674-0
|
Authors |
Vincent Conticello, Spencer Hughes, Charles Modlin, Conticello, Vincent, Hughes, Spencer, Modlin, Charles |
Abstract |
The development of biomaterials designed for specific applications is an important objective in personalized medicine. While the breadth and prominence of biomaterials have increased exponentially over the past decades, critical challenges remain to be addressed, particularly in the development of biomaterials that exhibit highly specific functions. These functional properties are often encoded within the molecular structure of the component molecules. Proteins, as a consequence of their structural specificity, represent useful substrates for the construction of functional biomaterials through rational design. This chapter provides an in-depth survey of biomaterials constructed from coiled-coils, one of the best-understood protein structural motifs. We discuss the utility of this structurally diverse and functionally tunable class of proteins for the creation of novel biomaterials. This discussion illustrates the progress that has been made in the development of coiled-coil biomaterials by showcasing studies that bridge the gap between the academic science and potential technological impact. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 26 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 23% |
Student > Ph. D. Student | 6 | 23% |
Other | 1 | 4% |
Student > Doctoral Student | 1 | 4% |
Student > Bachelor | 1 | 4% |
Other | 2 | 8% |
Unknown | 9 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 23% |
Chemistry | 5 | 19% |
Materials Science | 3 | 12% |
Medicine and Dentistry | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 1 | 4% |
Unknown | 9 | 35% |