| Chapter title |
Anterior Cruciate Ligament: Structure, Injuries and Regenerative Treatments.
|
|---|---|
| Chapter number | 10 |
| Book title |
Engineering Mineralized and Load Bearing Tissues
|
| Published in |
Advances in experimental medicine and biology, January 2015
|
| DOI | 10.1007/978-3-319-22345-2_10 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-922344-5, 978-3-31-922345-2
|
| Authors |
Negahi Shirazi, Ali, Chrzanowski, Wojciech, Khademhosseini, Ali, Dehghani, Fariba, Ali Negahi Shirazi, Wojciech Chrzanowski, Ali Khademhosseini, Fariba Dehghani |
| Abstract |
Anterior cruciate ligament (ACL) is one of the most vulnerable ligaments of the knee. ACL impairment results in episodic instability, chondral and meniscal injury and early osteoarthritis. The poor self-healing capacity of ACL makes surgical treatment inevitable. Current ACL reconstructions include a substitution of torn ACL via biological grafts such as autograft, allograft. This review provides an insight of ACL structure, orientation and properties followed by comparing the performance of various constructs that have been used for ACL replacement. New approaches, undertaken to induce ACL regeneration and fabricate biomimetic scaffolds, are also discussed. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 81 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 21 | 26% |
| Student > Master | 13 | 16% |
| Researcher | 7 | 9% |
| Lecturer | 4 | 5% |
| Student > Ph. D. Student | 4 | 5% |
| Other | 10 | 12% |
| Unknown | 22 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 16% |
| Nursing and Health Professions | 10 | 12% |
| Engineering | 10 | 12% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Other | 16 | 20% |
| Unknown | 25 | 31% |