Protein Amyloid Aggregation

Chapter 1 Semisynthesis and Enzymatic Preparation of Post-translationally Modified α-Synuclein.

Chapter 2 Isotope-Labeled Amyloids via Synthesis, Expression, and Chemical Ligation for Use in FTIR, 2D IR, and NMR Studies.

Chapter 3 Intermolecular Paramagnetic Relaxation Enhancement (PRE) Studies of Transient Complexes in Intrinsically Disordered Proteins.

Chapter 4 Detection of Helical Intermediates During Amyloid Formation by Intrinsically Disordered Polypeptides and Proteins.

Chapter 5 Fluorescence Correlation Spectroscopy: A Tool to Study Protein Oligomerization and Aggregation In Vitro and In Vivo.

Chapter 6 Deep UV Resonance Raman Spectroscopy for Characterizing Amyloid Aggregation

Chapter 7 Analyzing Tau Aggregation with Electron Microscopy.

Chapter 8 Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS).

Chapter 9 Formation and Characterization of α-Synuclein Oligomers.

Chapter 10 Fluorescence Methods for Unraveling Oligomeric Amyloid Intermediates

Chapter 11 Preparation of Amyloid Fibrils for Magic-Angle Spinning Solid-State NMR Spectroscopy

Chapter 12 Spin Labeling and Characterization of Tau Fibrils Using Electron Paramagnetic Resonance (EPR).

Chapter 13 Preparation of Crystalline Samples of Amyloid Fibrils and Oligomers

Chapter 14 Quenched Hydrogen Exchange NMR of Amyloid Fibrils

Chapter 15 Studying the Early Stages of Protein Aggregation Using Replica Exchange Molecular Dynamics Simulations

Chapter 16 Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels.

Chapter 17 Analyzing Ensembles of Amyloid Proteins Using Bayesian Statistics

Chapter 18 In Vitro Studies of Membrane Permeability Induced by Amyloidogenic Polypeptides Using Large Unilamellar Vesicles

Chapter 19 Cell Models to Study Cell-to-Cell Transmission of α-Synuclein.

Chapter 20 Preparation of Amyloid Fibrils Seeded from Brain and Meninges.