| Chapter title |
Neuropathic Pain: Sensory Nerve Injury or Motor Nerve Injury?
|
|---|---|
| Chapter number | 5 |
| Book title |
Translational Research in Pain and Itch
|
| Published in |
Advances in experimental medicine and biology, January 2016
|
| DOI | 10.1007/978-94-017-7537-3_5 |
| Pubmed ID | |
| Book ISBNs |
978-9-40-177535-9, 978-9-40-177537-3
|
| Authors |
Xian-Guo Liu, Rui-Ping Pang, Li-Jun Zhou, Xu-Hong Wei, Ying Zang, Liu, Xian-Guo, Pang, Rui-Ping, Zhou, Li-Jun, Wei, Xu-Hong, Zang, Ying |
| Abstract |
Peripheral nerve injury often induces chronic neuropathic pain. Peripheral nerve is consisted of sensory fibers and motor fibers, it is questioned injury to which type of fibers is responsible for generation of neuropathic pain? Because neuropathic pain is sensory disorder, it is generally believed that the disease should be induced by injury to sensory fibers. In recent years, however, emergent evidence shows that motor fiber injury but not sensory fiber injury is necessary and sufficient for induction of neuropathic pain. Motor fiber injury leads to neuropathic pain by upregulating pro-inflammatory cytokines and brain-derived neurotrophic factor in pain pathway. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 38 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 21% |
| Student > Master | 4 | 11% |
| Student > Bachelor | 4 | 11% |
| Student > Doctoral Student | 3 | 8% |
| Researcher | 3 | 8% |
| Other | 7 | 18% |
| Unknown | 9 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 32% |
| Neuroscience | 6 | 16% |
| Nursing and Health Professions | 3 | 8% |
| Engineering | 2 | 5% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 2 | 5% |
| Unknown | 12 | 32% |