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Reviews of Physiology, Biochemistry and Pharmacology, Vol. 173

Overview of attention for book
Attention for Chapter 2: Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases
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Chapter title
Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases
Chapter number 2
Book title
Reviews of Physiology, Biochemistry and Pharmacology, Vol. 173
Published in
Reviews of Physiology, Biochemistry and Pharmacology, April 2017
DOI 10.1007/112_2017_2
Pubmed ID
Book ISBNs
978-3-31-961366-6, 978-3-31-961367-3
Authors

Bastos, Pedro, Gomes, Tiago, Ribeiro, Laura, Pedro Bastos, Tiago Gomes, Laura Ribeiro

Abstract

Catechol-O-methyltransferase (COMT) is an enzyme that catalyses the methylation of catechol substrates, classically in catecholamine metabolism, but also acting upon other substrates such as oestrogen and polyphenols. Although its classical function has been established for more than five decades, an ever expanding COMT role in other pathways and diseases has become a subject of active study in recent years. The most highlighted domains are related with COMT involvement in neuropsychiatric disorders and its role in the neurobiology of cognition, behaviour, emotions, pain processing and perception, sleep regulation, addictive behaviour and neurodegeneration. Nonetheless, great attention is also being devoted to a possible COMT contribution to the development of cardiovascular disorders and hormonally influenced diseases, including cancer. This review aims to update the role of COMT function and its involvement in cardiovascular and neurological disorders.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 25%
Student > Master 11 15%
Student > Ph. D. Student 9 12%
Researcher 7 9%
Student > Doctoral Student 4 5%
Other 6 8%
Unknown 19 25%
Readers by discipline Count As %
Medicine and Dentistry 14 19%
Biochemistry, Genetics and Molecular Biology 13 17%
Psychology 7 9%
Nursing and Health Professions 4 5%
Agricultural and Biological Sciences 3 4%
Other 9 12%
Unknown 25 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2017.
All research outputs
#15,810,483
of 26,017,215 outputs
Outputs from Reviews of Physiology, Biochemistry and Pharmacology
#62
of 98 outputs
Outputs of similar age
#173,353
of 327,846 outputs
Outputs of similar age from Reviews of Physiology, Biochemistry and Pharmacology
#2
of 2 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 98 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,846 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.