Chapter title |
Role of brain tryptophan and serotonin in secondary anorexia.
|
---|---|
Chapter number | 26 |
Book title |
Developments in Tryptophan and Serotonin Metabolism
|
Published in |
Advances in experimental medicine and biology, June 2004
|
DOI | 10.1007/978-1-4615-0135-0_26 |
Pubmed ID | |
Book ISBNs |
978-1-4613-4939-6, 978-1-4615-0135-0
|
Authors |
Rossi-Fanelli F, Laviano A, Filippo Rossi-Fanelli, Alessandro Laviano, Rossi-Fanelli, Filippo, Laviano, Alessandro |
Abstract |
Anorexia and reduced energy intake contribute to worsen the prognosis of patients suffering from a number of chronic diseases, by promoting skeletal muscle wasting, leading to the development of malnutrition and eventually cachexia. The pathogenesis of cancer anorexia is still matter of debate. Many possible mediators, including hormones, peptides, and neurotransmitters, appear to be involved. However, consistent animal and clinical data suggest that brain tryptophan and serotonin may represent a common final pathway shared by many contributing factors. Supporting this hypothesis, recent data showed that the manipulation of brain tryptophan availability ameliorates anorexia and food intake in cancer patients. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor | 3 | 30% |
Student > Master | 2 | 20% |
Student > Bachelor | 1 | 10% |
Student > Doctoral Student | 1 | 10% |
Professor > Associate Professor | 1 | 10% |
Other | 1 | 10% |
Unknown | 1 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 30% |
Psychology | 2 | 20% |
Neuroscience | 1 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
Unknown | 3 | 30% |