Chapter title |
Pseudogene-Expressed RNAs: Emerging Roles in Gene Regulation and Disease.
|
---|---|
Chapter number | 442 |
Book title |
Long Non-coding RNAs in Human Disease
|
Published in |
Current topics in microbiology and immunology, May 2015
|
DOI | 10.1007/82_2015_442 |
Pubmed ID | |
Book ISBNs |
978-3-31-923906-4, 978-3-31-923907-1
|
Authors |
Grandér, Dan, Johnsson, Per, Dan Grandér, Per Johnsson |
Abstract |
Pseudogenes have for long been considered as non-functional relics littering the human genome. Only now, it is becoming apparent that many pseudogenes are transcribed into long noncoding RNAs, some with proven biological functions. Here, we review the current knowledge of pseudogenes and their widespread functional properties with an emphasis on pseudogenes that have been functionally investigated in greater detail. Pseudogenes are emerging as a novel class of long noncoding RNAs functioning, for example, through microRNA sponging and chromatin remodeling. The examples discussed herein underline that pseudogene-encoded RNAs are important regulatory molecules involved in diseases such as cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
France | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
Unknown | 33 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 32% |
Student > Doctoral Student | 3 | 9% |
Student > Bachelor | 3 | 9% |
Student > Ph. D. Student | 3 | 9% |
Student > Master | 3 | 9% |
Other | 5 | 15% |
Unknown | 6 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 8 | 24% |
Agricultural and Biological Sciences | 7 | 21% |
Medicine and Dentistry | 5 | 15% |
Neuroscience | 2 | 6% |
Immunology and Microbiology | 2 | 6% |
Other | 3 | 9% |
Unknown | 7 | 21% |