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Cancer Vaccines

Overview of attention for book
Cover of 'Cancer Vaccines'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Single-Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules
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    Chapter 2 Generation of Multiple Peptide Cocktail-Pulsed Dendritic Cells as a Cancer Vaccine
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    Chapter 3 Pulsing Dendritic Cells with Whole Tumor Cell Lysates
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    Chapter 4 Antigen Trapping by Dendritic Cells for Antitumor Therapy
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    Chapter 5 Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens
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    Chapter 6 Tumor antigen-/cytokine-pulsed dendritic cells in therapy against lymphoma.
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    Chapter 7 Dendritic Cells Primed with Protein–Protein Fusion Adjuvant
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    Chapter 8 Antigen-specific mRNA transfection of autologous dendritic cells.
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    Chapter 9 Electroporation of dendritic cells with autologous total RNA from tumor material.
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    Chapter 10 Dendritic Cells Transfected with Adenoviral Vectors as Vaccines
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    Chapter 11 Genetic Modification of Dendritic Cells with RNAi.
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    Chapter 12 Fast Monocyte-Derived Dendritic Cell-Based Immunotherapy
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    Chapter 13 Intratumoral Injection of BCG-CWS-Pretreated Dendritic Cells Following Tumor Cryoablation
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    Chapter 14 Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines.
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    Chapter 15 Modification of T lymphocytes to express tumor antigens.
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    Chapter 16 Genetic modification of mouse effector and helper T lymphocytes expressing a chimeric antigen receptor.
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    Chapter 17 Genetic modification of cytotoxic T lymphocytes to express cytokine receptors.
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    Chapter 18 Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients
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    Chapter 19 Cytokine activation of natural killer cells.
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    Chapter 20 Loading of Acute Myeloid Leukemia Cells with Poly(I:C) by Electroporation
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    Chapter 21 Autologous Tumor Cells Engineered to Express Bacterial Antigens
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    Chapter 22 Tumor Cell Transformation Using Antisense Oligonucleotide
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    Chapter 23 The direct display of costimulatory proteins on tumor cells as a means of vaccination for cancer immunotherapy.
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    Chapter 24 Cloning variable region genes of clonal lymphoma immunoglobulin for generating patient-specific idiotype DNA vaccine.
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    Chapter 25 Heat Shock Proteins Purified from Autologous Tumors Using Antibody-Based Affinity Chromatography
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    Chapter 26 Invariant Chain-Peptide Fusion Vaccine Using HER-2/neu
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    Chapter 27 TLR-9 Agonist Immunostimulatory Sequence Adjuvants Linked to Cancer Antigens.
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    Chapter 28 Production of Multiple CTL Epitopes from Multiple Tumor-Associated Antigens.
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    Chapter 29 Preparation of Polypeptides Comprising Multiple TAA Peptides.
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    Chapter 30 Idiotype Vaccine Production Using Hybridoma Technology
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    Chapter 31 Preparation of Cancer-Related Peptide Cocktails that Target Heterogeneously Expressed Antigens
  33. Altmetric Badge
    Chapter 32 Making an Avipoxvirus Encoding a Tumor-Associated Antigen and a Costimulatory Molecule
  34. Altmetric Badge
    Chapter 33 Bacterial vectors for the delivery of tumor antigens.
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    Chapter 34 Preparation of Peptide microspheres using tumor antigen-derived peptides.
  36. Altmetric Badge
    Chapter 35 Production of antigen-loaded biodegradable nanoparticles and uptake by dendritic cells.
  37. Altmetric Badge
    Chapter 36 Development of Plasmid–Lipid Complexes for Direct Intratumoral Injection
  38. Altmetric Badge
    Chapter 37 The use of dendritic cells for Peptide-based vaccination in cancer immunotherapy.
  39. Altmetric Badge
    Chapter 38 Advances in host and vector development for the production of plasmid DNA vaccines.
  40. Altmetric Badge
    Chapter 39 Challenges facing the development of cancer vaccines.
  41. Altmetric Badge
    Chapter 40 Future of cancer vaccines.
Attention for Chapter 14: Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines.
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Chapter title
Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines.
Chapter number 14
Book title
Cancer Vaccines
Published in
Methods in molecular biology, March 2014
DOI 10.1007/978-1-4939-0345-0_14
Pubmed ID
Book ISBNs
978-1-4939-0344-3, 978-1-4939-0345-0
Authors

Lameris R, Schneiders FL, de Gruijl TD, van der Vliet HJ, Roeland Lameris, Famke L. Schneiders, Tanja D. de Gruijl, Hans J. van der Vliet

Abstract

Invariant natural killer T cells (iNKT) and dendritic cells (DC) play a central role in tumor immunity through downstream activation of immune effector cells by pro-inflammatory cytokines. Evidence is accumulating that the CD1d-iNKT cell axis can be effectively used to potentiate DC-based cancer vaccines. Here, we provide a detailed methodology for the generation of (CD1d-expressing) monocyte-derived DC (moDC) and their subsequent loading with the iNKT cell agonist α-galactosylceramide (α-GalCer) or their direct ligation by agonistic anti-CD1d monoclonal antibodies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 3%
Switzerland 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 28%
Student > Ph. D. Student 6 15%
Student > Master 4 10%
Student > Doctoral Student 2 5%
Student > Bachelor 2 5%
Other 7 18%
Unknown 8 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 20%
Agricultural and Biological Sciences 6 15%
Immunology and Microbiology 6 15%
Medicine and Dentistry 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 3 8%
Unknown 12 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2014.
All research outputs
#18,369,403
of 22,751,628 outputs
Outputs from Methods in molecular biology
#7,861
of 13,088 outputs
Outputs of similar age
#160,818
of 220,996 outputs
Outputs of similar age from Methods in molecular biology
#53
of 160 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,088 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,996 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 160 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.