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Mendeley readers
| Chapter title |
Coupling Fluxes, Enzymes, and Regulation in Genome-Scale Metabolic Models
|
|---|---|
| Chapter number | 15 |
| Book title |
Metabolic Network Reconstruction and Modeling
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7528-0_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7527-3, 978-1-4939-7528-0
|
| Authors |
Paul A. Jensen |
| Abstract |
Genome-scale models have expanded beyond their metabolic origins. Multiple modeling frameworks are required to combine metabolism with enzymatic networks, transcription, translation, and regulation. Mathematical programming offers a powerful set of tools for tackling these "multi-modality" models, although special attention must be paid to the connections between modeling types. This chapter reviews common methods for combining metabolic and discrete logical models into a single mathematical programming framework. Best practices, caveats, and recommendations are presented for the most commonly used software packages. Methods for troubleshooting large sets of logical rules are also discussed. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 33% |
| Student > Master | 2 | 22% |
| Other | 1 | 11% |
| Student > Bachelor | 1 | 11% |
| Unknown | 2 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 22% |
| Biochemistry, Genetics and Molecular Biology | 1 | 11% |
| Chemistry | 1 | 11% |
| Unknown | 5 | 56% |