Chapter title |
Using PSAMM for the Curation and Analysis of Genome-Scale Metabolic Models
|
---|---|
Chapter number | 6 |
Book title |
Metabolic Network Reconstruction and Modeling
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7528-0_6 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7527-3, 978-1-4939-7528-0
|
Authors |
Keith Dufault-Thompson, Jon Lund Steffensen, Ying Zhang |
Abstract |
PSAMM is an open source software package that supports the iterative curation and analysis of genome-scale models (GEMs). It aims to integrate the annotation and consistency checking of metabolic models with the simulation of metabolic fluxes. The model representation in PSAMM is compatible with version tracking systems like Git, which allows for full documentation of model file changes and enables collaborative curations of large, complex models. This chapter provides a protocol for using PSAMM functions and a detailed description of the various aspects in setting up and using PSAMM for the simulation and analysis of metabolic models. The overall PSAMM workflow outlined in this chapter includes the import and export of model files, the documentation of model modifications using the Git version control system, the application of consistency checking functions for model curations, and the numerical simulation of metabolic models. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 33% |
Student > Ph. D. Student | 2 | 11% |
Student > Master | 2 | 11% |
Other | 1 | 6% |
Professor | 1 | 6% |
Other | 2 | 11% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 22% |
Agricultural and Biological Sciences | 3 | 17% |
Medicine and Dentistry | 2 | 11% |
Computer Science | 1 | 6% |
Environmental Science | 1 | 6% |
Other | 2 | 11% |
Unknown | 5 | 28% |