| Chapter title |
The parasympathetic nervous system as a regulator of mast cell function.
|
|---|---|
| Chapter number | 9 |
| Book title |
Mast Cells
|
| Published in |
Methods in molecular biology, November 2014
|
| DOI | 10.1007/978-1-4939-1568-2_9 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-1567-5, 978-1-4939-1568-2
|
| Authors |
Forsythe P, Paul Forsythe, Forsythe, Paul |
| Abstract |
Often considered as the archetype of neuroimmune communication, much of our understanding of the bidirectional relationship between the nervous and immune systems has come from the study of mast cell-nerve interaction. Mast cells play a role in resistance to infection and are extensively involved in inflammation and subsequent tissue repair. Thus, the relationship between mast cells and neurons enables the involvement of peripheral and central nervous systems in the regulation of host defense mechanisms and inflammation.Recently, with the identification of the cholinergic anti-inflammatory pathway, there has been increased interest in the role of the parasympathetic nervous system in regulating immune responses. Classical neurotransmitters and neuropeptides released from cholinergic and inhibitory NANC neurons can modulate mast cell activity, and there is good evidence for the existence of parasympathetic nerve-mast cell functional units in the skin, lung, and intestine that have the potential to regulate a range of physiological processes. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 27% |
| United Kingdom | 1 | 9% |
| Unknown | 7 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 55% |
| Scientists | 3 | 27% |
| Practitioners (doctors, other healthcare professionals) | 2 | 18% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 15% |
| Student > Bachelor | 4 | 15% |
| Researcher | 3 | 12% |
| Other | 2 | 8% |
| Student > Ph. D. Student | 2 | 8% |
| Other | 4 | 15% |
| Unknown | 7 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 15% |
| Psychology | 3 | 12% |
| Immunology and Microbiology | 3 | 12% |
| Nursing and Health Professions | 2 | 8% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Other | 4 | 15% |
| Unknown | 9 | 35% |