Chapter title |
Assay of mast cell mediators.
|
---|---|
Chapter number | 19 |
Book title |
Mast Cells
|
Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-1568-2_19 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1567-5, 978-1-4939-1568-2
|
Authors |
Madeleine Rådinger, Bettina M Jensen, Emily Swindle, Alasdair M Gilfillan, Bettina M. Jensen, Alasdair M. Gilfillan, Rådinger, Madeleine, Jensen, Bettina M., Swindle, Emily, Gilfillan, Alasdair M. |
Abstract |
Mediator release from activated mast cells is a major initiator of the symptomology associated with allergic disorders such as anaphylaxis and asthma. Thus, methods to monitor the generation and release of such mediators have widespread applicability in studies designed to understand the processes regulating mast cell activation and for the identification of therapeutic approaches to block mast cell-driven disease. In this chapter, we discuss approaches used for the determination of mast cell degranulation, lipid-derived inflammatory mediator production, and cytokine/chemokine gene expression as well as cytokine release. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 24% |
Student > Bachelor | 3 | 14% |
Researcher | 2 | 10% |
Student > Master | 2 | 10% |
Unknown | 9 | 43% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 3 | 14% |
Biochemistry, Genetics and Molecular Biology | 2 | 10% |
Agricultural and Biological Sciences | 2 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Other | 3 | 14% |
Unknown | 9 | 43% |