Chapter title |
C/EBPB-CITED4 in Exercised Heart
|
---|---|
Chapter number | 14 |
Book title |
Exercise for Cardiovascular Disease Prevention and Treatment
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-981-10-4304-8_14 |
Pubmed ID | |
Book ISBNs |
978-9-81-104303-1, 978-9-81-104304-8
|
Authors |
Shengguang Ding, Tianyi Gan, Meiyi Song, Qiying Dai, Haitao Huang, Yiming Xu, Chongjun Zhong |
Abstract |
C/EBPB is a crucial transcription factor, participating in a variety of biological processes including cell proliferation, differentiation and development. In the cardiovascular system, C/EBPB-CITED4 signaling is known as a signaling pathway mediating exercise-induced cardiac growth. After its exact role in exercised heart firstly reported in 2010, more and more evidence confirmed that. MicroRNA (e.g. miR-222) and many molecules (e.g. Alpha-lipoic acid) can regulate this pathway and then involve in the cardiac protection effect induced by endurance exercise training. In addition, in cardiac growth during pregnancy, C/EBPB is also a required regulator. This chapter will give an introduction of the C/EBPB-CITED4 signaling and the regulatory network based on this signaling pathway in exercised heart. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 22% |
Student > Bachelor | 3 | 13% |
Student > Doctoral Student | 2 | 9% |
Student > Master | 2 | 9% |
Lecturer | 1 | 4% |
Other | 2 | 9% |
Unknown | 8 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 13% |
Medicine and Dentistry | 2 | 9% |
Chemistry | 2 | 9% |
Neuroscience | 2 | 9% |
Social Sciences | 1 | 4% |
Other | 3 | 13% |
Unknown | 10 | 43% |