| Chapter title |
Stem Cells in Regenerative Cardiology
|
|---|---|
| Chapter number | 113 |
| Book title |
Advances in Experimental Medicine and Biology
|
| Published in |
Advances in experimental medicine and biology, October 2017
|
| DOI | 10.1007/5584_2017_113 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-993866-0, 978-3-31-993867-7
|
| Authors |
Semih Arbatlı, Galip Servet Aslan, Fatih Kocabaş, Arbatlı, Semih, Aslan, Galip Servet, Kocabaş, Fatih |
| Abstract |
The common prevalence of heart failure and limitations in its treatment are leading cause of attention and interest towards the induction of cardiac regeneration with novel approaches. Recent studies provide growing evidence regarding bona fide cardiac regeneration post genetic manipulations, administration of stimulatory factors and myocardial injuries in animal models and human studies. To this end, stem cells of different sources have been tested to treat heart failure for the development of cellular therapies. Endogenous and exogenous stem cells sources used in regenerative cardiology have provided a proof of concept and applicability of cellular therapies in myocardial improvement. Recent clinical studies, especially, based on the endogenous cardiac progenitor and stem cells highlighted the possibility to regenerate lost cardiomyocytes in the myocardium. This review discusses emerging concepts in cardiac stem cell therapy, their sources and route of administration, and plausibility of de novo cardiomyocyte formation. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Turkey | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 31% |
| Researcher | 2 | 15% |
| Student > Ph. D. Student | 2 | 15% |
| Student > Bachelor | 1 | 8% |
| Student > Doctoral Student | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 3 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 5 | 38% |
| Medicine and Dentistry | 2 | 15% |
| Veterinary Science and Veterinary Medicine | 1 | 8% |
| Unknown | 5 | 38% |