Chapter title |
l -Methionine Production
|
---|---|
Chapter number | 30 |
Book title |
Amino Acid Fermentation
|
Published in |
Advances in biochemical engineering biotechnology, January 2016
|
DOI | 10.1007/10_2016_30 |
Pubmed ID | |
Book ISBNs |
978-4-43-156518-5, 978-4-43-156520-8
|
Authors |
Jihyun Shim, Yonguk Shin, Imsang Lee, So Young Kim, Shim, Jihyun, Shin, Yonguk, Lee, Imsang, Kim, So Young |
Abstract |
L-Methionine has been used in various industrial applications such as the production of feed and food additives and has been used as a raw material for medical supplies and drugs. It functions not only as an essential amino acid but also as a physiological effector, for example, by inhibiting fat accumulation and enhancing immune response. Producing methionine from fermentation is beneficial in that microorganisms can produce L-methionine selectively using eco-sustainable processes. Nevertheless, the fermentative method has not been used on an industrial scale because it is not competitive economically compared with chemical synthesis methods. Presented are efforts to develop suitable strains, engineered enzymes, and alternative process of producing L-methionine that overcomes problems of conventional fermentation methods. One of the alternative processes is a two-step process in which the L-methionine precursor is produced by fermentation and then converted to L-methionine by enzymes. Directed efforts toward strain development and enhanced enzyme engineering will advance industrial production of L-methionine based on fermentation. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
China | 1 | 2% |
Unknown | 41 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 21% |
Student > Bachelor | 7 | 16% |
Student > Ph. D. Student | 6 | 14% |
Student > Master | 3 | 7% |
Professor | 2 | 5% |
Other | 4 | 9% |
Unknown | 12 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 12 | 28% |
Agricultural and Biological Sciences | 7 | 16% |
Environmental Science | 2 | 5% |
Immunology and Microbiology | 2 | 5% |
Engineering | 2 | 5% |
Other | 7 | 16% |
Unknown | 11 | 26% |