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Pharmacology of Mitochondria

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Cover of 'Pharmacology of Mitochondria'

Table of Contents

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    Book Overview
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    Chapter 1 Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways
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    Chapter 1 The Mitochondrial Ca2+ Uniporter: Structure, Function, and Pharmacology
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    Chapter 2 Toxicity of Antiepileptic Drugs to Mitochondria
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    Chapter 2 Leber Hereditary Optic Neuropathy: Exemplar of an mtDNA Disease
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    Chapter 3 Nuclear Transcription Factors in the Mitochondria: A New Paradigm in Fine-Tuning Mitochondrial Metabolism
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    Chapter 3 Mitochondria in Alzheimer’s Disease and Diabetes-Associated Neurodegeneration: License to Heal!
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    Chapter 4 MITO-Porter for Mitochondrial Delivery and Mitochondrial Functional Analysis
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    Chapter 5 The Mitochondrial Permeability Transition Pore and ATP Synthase
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    Chapter 6 The Emerging Role of Mitochondrial Targeting in Kidney Disease
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    Chapter 7 Mitochondrial Dynamics as a Therapeutic Target for Treating Cardiac Diseases
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    Chapter 37 Mitochondria-Targeted Agents: Mitochondriotropics, Mitochondriotoxics, and Mitocans
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    Chapter 38 Mitochondrial Fission in Human Diseases
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    Chapter 39 Anion Channels of Mitochondria
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    Chapter 40 Mitochondrial Changes in Cancer
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    Chapter 79 Guide to the Pharmacology of Mitochondrial Potassium Channels
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    Chapter 87 Erratum to: The Mitochondrial Permeability Transition Pore and ATP Synthase
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    Chapter 92 The Roles of Mitochondrial Cation Channels Under Physiological Conditions and in Cancer
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    Chapter 93 Equipping Physiologists with an Informatics Tool Chest: Toward an Integerated Mitochondrial Phenome
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    Chapter 110 Mitochondrial Cholesterol and the Paradox in Cell Death
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    Chapter 117 Role of Mitochondrial Reactive Oxygen Species in the Activation of Cellular Signals, Molecules, and Function
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    Chapter 129 Mitochondrial Flashes: Elemental Signaling Events in Eukaryotic Cells
Attention for Chapter 93: Equipping Physiologists with an Informatics Tool Chest: Toward an Integerated Mitochondrial Phenome
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Citations

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Chapter title
Equipping Physiologists with an Informatics Tool Chest: Toward an Integerated Mitochondrial Phenome
Chapter number 93
Book title
Pharmacology of Mitochondria
Published in
Handbook of experimental pharmacology, January 2016
DOI 10.1007/164_2016_93
Pubmed ID
Book ISBNs
978-3-31-957311-3, 978-3-31-957313-7
Authors

Anders Olav Garlid, Jennifer S. Polson, Keith D. Garlid, Henning Hermjakob, Peipei Ping

Abstract

Understanding the complex involvement of mitochondrial biology in disease development often requires the acquisition, analysis, and integration of large-scale molecular and phenotypic data. An increasing number of bioinformatics tools are currently employed to aid in mitochondrial investigations, most notably in predicting or corroborating the spatial and temporal dynamics of mitochondrial molecules, in retrieving structural data of mitochondrial components, and in aggregating as well as transforming mitochondrial centric biomedical knowledge. With the increasing prevalence of complex Big Data from omics experiments and clinical cohorts, informatics tools have become indispensable in our quest to understand mitochondrial physiology and pathology. Here we present an overview of the various informatics resources that are helping researchers explore this vital organelle and gain insights into its form, function, and dynamics.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 33%
Lecturer 2 13%
Researcher 2 13%
Student > Bachelor 1 7%
Professor 1 7%
Other 1 7%
Unknown 3 20%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 27%
Computer Science 3 20%
Engineering 2 13%
Agricultural and Biological Sciences 2 13%
Business, Management and Accounting 1 7%
Other 0 0%
Unknown 3 20%