Chapter title |
Cardioprotective Effects of Exosomes and Their Potential Therapeutic Use
|
---|---|
Chapter number | 11 |
Book title |
Exosomes in Cardiovascular Diseases
|
Published in |
Advances in experimental medicine and biology, January 2017
|
DOI | 10.1007/978-981-10-4397-0_11 |
Pubmed ID | |
Book ISBNs |
978-9-81-104396-3, 978-9-81-104397-0
|
Authors |
Shengguang Ding, Jingying Zhang, Qiying Dai, Mengfei Zhao, Haitao Huang, Yiming Xu, Chongjun Zhong |
Abstract |
Exosomes are membrane-contained vesicles released by various types of cells both in animals and human. They contain microRNAs and proteins and can travel to target cells, affecting their functions. There are specific factors on the surface of every exosomes, making sure that they will be taken up by certain type of cells. With these features, exosomes have been recognized to be one of the fundamental "messengers" for cell-cell communication. Recently, increased interest has been raised in exosomes since they were discovered to play an unneglectable role in preserving cardiac function and cardiomyocyte repair during stress. The widely explored stem cell therapy for cardiomyopathy uncovered the contribution of exosomes. Here we summarized cardioprotective effects of exosomes and their potential therapeutic use. |
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