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Behavioral Neuroscience of Orexin/Hypocretin

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Attention for Chapter 59: The Hypocretin/Orexin Neuronal Networks in Zebrafish
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Chapter title
The Hypocretin/Orexin Neuronal Networks in Zebrafish
Chapter number 59
Book title
Behavioral Neuroscience of Orexin/Hypocretin
Published in
Current topics in behavioral neurosciences, January 2016
DOI 10.1007/7854_2016_59
Pubmed ID
Book ISBNs
978-3-31-957534-6, 978-3-31-957535-3
Authors

Idan Elbaz, Talia Levitas-Djerbi, Lior Appelbaum

Abstract

The hypothalamic Hypocretin/Orexin (Hcrt) neurons secrete two Hcrt neuropeptides. These neurons and peptides play a major role in the regulation of feeding, sleep wake cycle, reward-seeking, addiction, and stress. Loss of Hcrt neurons causes the sleep disorder narcolepsy. The zebrafish has become an attractive model to study the Hcrt neuronal network because it is a transparent vertebrate that enables simple genetic manipulation, imaging of the structure and function of neuronal circuits in live animals, and high-throughput monitoring of behavioral performance during both day and night. The zebrafish Hcrt network comprises ~16-60 neurons, which similar to mammals, are located in the hypothalamus and widely innervate the brain and spinal cord, and regulate various fundamental behaviors such as feeding, sleep, and wakefulness. Here we review how the zebrafish contributes to the study of the Hcrt neuronal system molecularly, anatomically, physiologically, and pathologically.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
Unknown 44 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 16%
Researcher 4 9%
Professor 4 9%
Student > Bachelor 4 9%
Student > Doctoral Student 3 7%
Other 11 24%
Unknown 12 27%
Readers by discipline Count As %
Neuroscience 10 22%
Agricultural and Biological Sciences 7 16%
Biochemistry, Genetics and Molecular Biology 4 9%
Medicine and Dentistry 4 9%
Social Sciences 2 4%
Other 4 9%
Unknown 14 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2017.
All research outputs
#15,477,045
of 22,999,744 outputs
Outputs from Current topics in behavioral neurosciences
#324
of 498 outputs
Outputs of similar age
#232,121
of 394,589 outputs
Outputs of similar age from Current topics in behavioral neurosciences
#54
of 67 outputs
Altmetric has tracked 22,999,744 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 498 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,589 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.