Chapter title |
A mathematical model of pH(i) regulation in central CO2- chemoreception.
|
---|---|
Chapter number | 53 |
Book title |
Integration in Respiratory Control
|
Published in |
Advances in experimental medicine and biology, January 2008
|
DOI | 10.1007/978-0-387-73693-8_53 |
Pubmed ID | |
Book ISBNs |
978-0-387-73692-1, 978-0-387-73693-8
|
Authors |
Juan M Cordovez, Chris Clausen, Leon C Moore, Irene C Solomon, Cordovez, Juan M, Clausen, Chris, Moore, Leon C, Solomon, Irene C, Juan M. Cordovez, Leon C. Moore, Irene C. Solomon, Cordovez, Juan M., Moore, Leon C., Solomon, Irene C. |
Abstract |
In CO2 chemosensitive neurons, an increase in CO2 (hypercapnia) leads to a maintained reduction in intracellular pH (pH(i)) while in non-chemosensitive neurons pH(i) recovery is observed. The precise mechanisms for the differential regulation of pH(i) recovery between these cell populations remain to be identified; however, studies have begun to explore the role of Na+/H+ exchange (NHE). Here, we compare the results of two different formulations of a mathematical model to begin to explore pH(i) regulation in central CO2 chemoreception. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 50% |
Student > Bachelor | 1 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 1 | 50% |
Engineering | 1 | 50% |