Chapter title |
Envelope Structures of Gram-Positive Bacteria
|
---|---|
Chapter number | 5021 |
Book title |
Protein and Sugar Export and Assembly in Gram-positive Bacteria
|
Published in |
Current topics in microbiology and immunology, January 2015
|
DOI | 10.1007/82_2015_5021 |
Pubmed ID | |
Book ISBNs |
978-3-31-956012-0, 978-3-31-956014-4
|
Authors |
Mithila Rajagopal, Suzanne Walker, Rajagopal M, Walker S, Rajagopal, Mithila, Walker, Suzanne |
Abstract |
Gram-positive organisms, including the pathogens Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis, have dynamic cell envelopes that mediate interactions with the environment and serve as the first line of defense against toxic molecules. Major components of the cell envelope include peptidoglycan (PG), which is a well-established target for antibiotics, teichoic acids (TAs), capsular polysaccharides (CPS), surface proteins, and phospholipids. These components can undergo modification to promote pathogenesis, decrease susceptibility to antibiotics and host immune defenses, and enhance survival in hostile environments. This chapter will cover the structure, biosynthesis, and important functions of major cell envelope components in gram-positive bacteria. Possible targets for new antimicrobials will be noted. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Canada | 1 | <1% |
Unknown | 337 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 48 | 14% |
Student > Bachelor | 43 | 13% |
Student > Master | 35 | 10% |
Student > Doctoral Student | 25 | 7% |
Researcher | 24 | 7% |
Other | 23 | 7% |
Unknown | 140 | 41% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 70 | 21% |
Immunology and Microbiology | 31 | 9% |
Agricultural and Biological Sciences | 27 | 8% |
Chemistry | 15 | 4% |
Medicine and Dentistry | 14 | 4% |
Other | 27 | 8% |
Unknown | 154 | 46% |