| Chapter title |
Type III Secreted Virulence Factors Manipulating Signaling to Actin Dynamics
|
|---|---|
| Chapter number | 35 |
| Book title |
The Actin Cytoskeleton and Bacterial Infection
|
| Published in |
Current topics in microbiology and immunology, January 2016
|
| DOI | 10.1007/82_2016_35 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-950046-1, 978-3-31-950047-8
|
| Authors |
Theresia E. B. Stradal, Sonia C. P. Costa |
| Abstract |
A key aspect of bacterial pathogenesis is the colonization and persistence within the host and, later on, its dissemination to new niches. During evolution, bacteria developed a myriad of virulence mechanisms to usurp the host's sophisticated defense mechanisms in order to establish their colonization niche. Elucidation of the highly dynamic and complex interactions between host and pathogens remains an important field of study. Here, we highlight the conserved manipulation of the actin cytoskeleton by some Gram-negative gastrointestinal pathogens, addressing the role of type III secreted bacterial GEFs at the different steps of pathogenesis. As a final topic, we review cytoskeleton dynamics induced by EPEC/EHEC strains for pedestal formation. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 9 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 33% |
| Lecturer > Senior Lecturer | 1 | 11% |
| Student > Doctoral Student | 1 | 11% |
| Student > Ph. D. Student | 1 | 11% |
| Student > Bachelor | 1 | 11% |
| Other | 2 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 3 | 33% |
| Biochemistry, Genetics and Molecular Biology | 2 | 22% |
| Physics and Astronomy | 1 | 11% |
| Medicine and Dentistry | 1 | 11% |
| Unknown | 2 | 22% |