| Chapter title |
Dopamine-based reward circuitry responsivity, genetics, and overeating.
|
|---|---|
| Chapter number | 89 |
| Book title |
Behavioral Neurobiology of Eating Disorders
|
| Published in |
Current topics in behavioral neurosciences, January 2011
|
| DOI | 10.1007/7854_2010_89 |
| Pubmed ID | |
| Book ISBNs |
978-3-64-215130-9, 978-3-64-215131-6
|
| Authors |
Stice E, Yokum S, Zald D, Dagher A, Eric Stice, Sonja Yokum, David Zald, Alain Dagher |
| Editors |
Roger A.H. Adan, Walter H. Kaye |
| Abstract |
Data suggest that low levels of dopamine D2 receptors and attenuated responsivity of dopamine-target regions to food intake is associated with increased eating and elevated weight. There is also growing (although mixed) evidence that genotypes that appear to lead to reduced dopamine signaling (e.g., DRD2, DRD4, and DAT) and certain appetite-related hormones and peptides (e.g., ghrelin, orexin A, leptin) moderate the relation between dopamine signaling, overeating, and obesity. This chapter reviews findings from studies that have investigated the relation between dopamine functioning and food intake and how certain genotypes and appetite-related hormones and peptides affect this relation. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | 3% |
| United States | 1 | <1% |
| Ethiopia | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 100 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 21 | 20% |
| Student > Ph. D. Student | 18 | 17% |
| Student > Master | 16 | 15% |
| Student > Bachelor | 9 | 8% |
| Professor | 9 | 8% |
| Other | 20 | 19% |
| Unknown | 13 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 25 | 24% |
| Medicine and Dentistry | 24 | 23% |
| Neuroscience | 13 | 12% |
| Agricultural and Biological Sciences | 10 | 9% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Other | 11 | 10% |
| Unknown | 20 | 19% |