| Chapter title |
Common Themes in Cytoskeletal Remodeling by Intracellular Bacterial Effectors
|
|---|---|
| Chapter number | 42 |
| Book title |
The Actin Cytoskeleton
|
| Published in |
Handbook of experimental pharmacology, January 2016
|
| DOI | 10.1007/164_2016_42 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-946369-8, 978-3-31-946371-1
|
| Authors |
Guy Tran Van Nhieu, Stéphane Romero |
| Editors |
Brigitte M. Jockusch |
| Abstract |
Bacterial pathogens interact with various types of tissues to promote infection. Because it controls the formation of membrane extensions, adhesive processes, or the junction integrity, the actin cytoskeleton is a key target of pathogens during infection. We will highlight common and specific functions of the actin cytoskeleton during bacterial infections, by first reviewing the mechanisms of intracellular motility of invasive Shigella, Listeria, and Rickettsia. Through the models of EPEC/EHEC, Shigella, Salmonella, and Chlamydia spp., we will illustrate various strategies of diversion of actin cytoskeletal processes used by these bacteria to colonize or breach epithelial/endothelial barriers. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 18% |
| Professor | 2 | 18% |
| Lecturer > Senior Lecturer | 1 | 9% |
| Student > Doctoral Student | 1 | 9% |
| Student > Master | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 3 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 1 | 9% |
| Mathematics | 1 | 9% |
| Agricultural and Biological Sciences | 1 | 9% |
| Immunology and Microbiology | 1 | 9% |
| Chemistry | 1 | 9% |
| Other | 1 | 9% |
| Unknown | 5 | 45% |