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Mendeley readers
| Chapter title |
RNA-Mediated Gene Activation: Identifying a Candidate RNA for Preclinical Development
|
|---|---|
| Chapter number | 11 |
| Book title |
RNA Activation
|
| Published in |
Advances in experimental medicine and biology, June 2017
|
| DOI | 10.1007/978-981-10-4310-9_11 |
| Pubmed ID | |
| Book ISBNs |
978-9-81-104309-3, 978-9-81-104310-9
|
| Authors |
David R. Corey |
| Editors |
Long-Cheng Li |
| Abstract |
The ability to activate gene expression would provide new opportunities for drug development for diseases caused by inadequate or nonexistent expression of a therapeutic protein. Duplex RNAs that target gene promoters are one strategy for enhancing the expression of target genes. This chapter summarizes our understanding of mechanism behind gene activation by small RNAs that bind noncoding transcripts at gene promoters. We describe a path for choosing candidate genes for therapeutic development. |
Mendeley readers
The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 1 | 33% |
| Other | 1 | 33% |
| Student > Doctoral Student | 1 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 67% |
| Agricultural and Biological Sciences | 1 | 33% |