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Mendeley readers
| Chapter title |
Preparation of a Two-Photon Fluorescent Probe for Imaging H2O2 in Lysosomes in Living Cells and Tissues
|
|---|---|
| Chapter number | 7 |
| Book title |
Lysosomes
|
| Published in |
Methods in molecular biology, April 2017
|
| DOI | 10.1007/978-1-4939-6934-0_7 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6932-6, 978-1-4939-6934-0
|
| Authors |
Mingguang Ren, Beibei Deng, Xiuqi Kong, Yonghe Tang, Weiying Lin |
| Editors |
Karin Öllinger, Hanna Appelqvist |
| Abstract |
Hydrogen peroxide (H2O2) plays important roles in many physiological and pathological processes. At the cellular organelle level, the abnormal concentrations of H2O2 in the lysosomes may cause redox imbalance and the loss of the critical functions of the lysosomes. Herein, we describe the preparation of a potent lysosome-targeted two-photon fluorescent probe (Lyso-HP) for the detection of H2O2 in the lysosomes in the living cells. This unique fluorescent probe can also be employed to effectively detect H2O2 in the living tissues using two-photon fluorescence microscopy. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 1 | 20% |
| Researcher | 1 | 20% |
| Student > Master | 1 | 20% |
| Unknown | 2 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 2 | 40% |
| Neuroscience | 1 | 20% |
| Unknown | 2 | 40% |