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Chapter title |
Protein Translocation Assays to Probe Protease Function and Screen for Inhibitors
|
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Chapter number | 17 |
Book title |
Protein Terminal Profiling
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Published in |
Methods in molecular biology, March 2017
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DOI | 10.1007/978-1-4939-6850-3_17 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6849-7, 978-1-4939-6850-3
|
Authors |
Angelina Hahlbrock, Dorothée Gößwein, Roland H. Stauber |
Editors |
Oliver Schilling |
Abstract |
In this chapter, you will learn how to use translocation biosensors to investigate protease functions in living cells. We here present modular protein translocation biosensors tailored to investigate protease activity and protein-protein interactions. Besides the mapping of protease function, the biosensors are also applicable to identify chemicals and/or (nano)materials modulating the respective protein activities and can also be exploited for RNAi-mediated genetic screens. |
Mendeley readers
The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Unspecified | 1 | 100% |
Readers by discipline | Count | As % |
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Unspecified | 1 | 100% |