Quasispecies: From Theory to Experimental Systems
Springer International Publishing
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Timeline
Mendeley readers
| Chapter title |
Quasispecies on Fitness Landscapes
|
|---|---|
| Chapter number | 469 |
| Book title |
Quasispecies: From Theory to Experimental Systems
|
| Published in |
Current topics in microbiology and immunology, January 2015
|
| DOI | 10.1007/82_2015_469 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-923897-5, 978-3-31-923898-2
|
| Authors |
Peter Schuster, Schuster, Peter |
| Abstract |
Selection-mutation dynamics is studied as adaptation and neutral drift on abstract fitness landscapes. Various models of fitness landscapes are introduced and analyzed with respect to the stationary mutant distributions adopted by populations upon them. The concept of quasispecies is introduced, and the error threshold phenomenon is analyzed. Complex fitness landscapes with large scatter of fitness values are shown to sustain error thresholds. The phenomenological theory of the quasispecies introduced in 1971 by Eigen is compared to approximation-free numerical computations. The concept of strong quasispecies understood as mutant distributions, which are especially stable against changes in mutations rates, is presented. The role of fitness neutral genotypes in quasispecies is discussed. |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 23% |
| Student > Master | 3 | 14% |
| Student > Ph. D. Student | 3 | 14% |
| Professor > Associate Professor | 2 | 9% |
| Professor | 2 | 9% |
| Other | 2 | 9% |
| Unknown | 5 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 27% |
| Medicine and Dentistry | 4 | 18% |
| Immunology and Microbiology | 3 | 14% |
| Agricultural and Biological Sciences | 2 | 9% |
| Chemical Engineering | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 5 | 23% |