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Mendeley readers
Chapter title |
Identification of Tau Toxicity Modifiers in the Drosophila Eye.
|
---|---|
Chapter number | 26 |
Book title |
Tau Protein
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Published in |
Methods in molecular biology, January 2017
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DOI | 10.1007/978-1-4939-6598-4_26 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6596-0, 978-1-4939-6598-4
|
Authors |
Pierre Dourlen |
Editors |
Caroline Smet-Nocca |
Abstract |
Drosophila is a powerful model to study human diseases thanks to its genetic tools and ease of screening. Human genes can be expressed in targeted organs and their toxicity assessed on easily scorable external phenotypes that can be used as readout to perform genetic screen of toxicity modifiers. In this chapter, I describe how to express human Tau protein in the Drosophila eye, assess protein expression by western blot, assess Tau toxicity by quantifying the size of the Tau-induced rough eye, and perform a genetic screen of modifiers of Tau toxicity in the Drosophila eye. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 2 | 22% |
Student > Doctoral Student | 1 | 11% |
Student > Ph. D. Student | 1 | 11% |
Student > Bachelor | 1 | 11% |
Researcher | 1 | 11% |
Other | 1 | 11% |
Unknown | 2 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 4 | 44% |
Agricultural and Biological Sciences | 1 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 11% |
Medicine and Dentistry | 1 | 11% |
Engineering | 1 | 11% |
Other | 0 | 0% |
Unknown | 1 | 11% |