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Genome Editing in Animals

Overview of attention for book
Cover of 'Genome Editing in Animals'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Construction and Evaluation of Zinc Finger Nucleases
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    Chapter 2 Updated Overview of TALEN Construction Systems
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    Chapter 3 CRISPR/Cas9
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    Chapter 4 SNPD-CRISPR: Single Nucleotide Polymorphism-Distinguishable Repression or Enhancement of a Target Gene Expression by CRISPR System.
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    Chapter 5 Utilizing Large Functional and Population Genomics Resources for CRISPR/Cas Perturbation Experiment Design.
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    Chapter 6 Generation of Genome-Edited Mice by Cytoplasmic Injection of CRISPR-Cas9 RNA
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    Chapter 7 Gene Targeting in Mouse Embryonic Stem Cells via CRISPR/Cas9 Ribonucleoprotein (RNP)-Mediated Genome Editing
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    Chapter 8 Generation of Knock-In Mouse by Genome Editing
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    Chapter 9 Introduction of Genetic Mutations Into Mice by Base Editor and Target-AID
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    Chapter 10 Genome Editing in Mouse and Rat by Electroporation.
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    Chapter 11 Generation of Floxed Mice by Sequential Electroporation
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    Chapter 12 Efficient Detection of Flox Mice Using In Vitro Cre Recombination
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    Chapter 13 VCre/VloxP and SCre/SloxP as Reliable Site-Specific Recombination Systems for Genome Engineering
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    Chapter 14 Efficient CRISPR/Cas9-Assisted Knockin of Large DNA Donors by Pronuclear Microinjection During S-Phase in Mouse Zygotes
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    Chapter 15 Genome Editing of Murine Liver Hepatocytes by AAV Vector-Mediated Expression of Cas9 In Vivo.
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    Chapter 16 Nonviral Ex Vivo Genome Editing in Mouse Bona Fide Hematopoietic Stem Cells with CRISPR/Cas9.
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    Chapter 17 Genome Editing of Rat.
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    Chapter 18 A Simple and Efficient Method for Generating KO Rats Using In Vitro Fertilized Oocytes
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    Chapter 19 Editing the Genome of the Golden Hamster (Mesocricetus auratus)
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    Chapter 20 Gene Targeting in Rabbits: Single-Step Generation of Knockout Rabbits by Microinjection of CRISPR/Cas9 Plasmids
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    Chapter 21 Genome Editing of Pig
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    Chapter 22 GEEP Method: An Optimized Electroporation-Mediated Gene Editing Approach for Establishment of Knockout Pig Lines
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    Chapter 23 Genome Editing Mediated by Primordial Germ Cell in Chicken.
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    Chapter 24 CRISPR-Cas9-Mediated Genome Modifications in Zebrafish.
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    Chapter 25 Genome Editing of Medaka
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    Chapter 26 CRISPR-Cas9-Based Functional Analysis in Amphibians: Xenopus laevis, Xenopus tropicalis, and Pleurodeles waltl.
  28. Altmetric Badge
    Chapter 27 Genome Editing of Silkworms
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    Chapter 28 Improved Genome Editing in the Ascidian Ciona with CRISPR/Cas9 and TALEN
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    Chapter 29 Genome Editing of C. elegans.
Attention for Chapter 29: Genome Editing of C. elegans.
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  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

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Chapter title
Genome Editing of C. elegans.
Chapter number 29
Book title
Genome Editing in Animals
Published in
Methods in molecular biology, January 2023
DOI 10.1007/978-1-0716-3016-7_29
Pubmed ID
Book ISBNs
978-1-07-163015-0, 978-1-07-163016-7
Authors

Sugi, Takuma

Abstract

Caenorhabditis elegans, a 1 mm long free-living nematode, is a traditional model animal for genetic investigations of various biological processes. Characteristic features that make C. elegans a powerful model of choice for eukaryotic genetic studies include its rapid life cycle, well-annotated genome, simple morphology, and transparency. Recently, genome editing technologies have been increasingly used in C. elegans, thereby facilitating their genetic analyses. Here, I introduce a protocol frequently used in C. elegans genome editing.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2023.
All research outputs
#15,727,781
of 25,359,594 outputs
Outputs from Methods in molecular biology
#4,451
of 14,186 outputs
Outputs of similar age
#221,182
of 478,041 outputs
Outputs of similar age from Methods in molecular biology
#164
of 722 outputs
Altmetric has tracked 25,359,594 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,186 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 478,041 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 722 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.