| Chapter title |
Ayahuasca for the Treatment of Depression
|
|---|---|
| Chapter number | 277 |
| Book title |
Disruptive Psychopharmacology
|
| Published in |
Current topics in behavioral neurosciences, January 2021
|
| DOI | 10.1007/7854_2021_277 |
| Pubmed ID | |
| Book ISBNs |
978-3-03-112183-8, 978-3-03-112184-5
|
| Authors |
Palhano-Fontes, Fernanda, Soares, Bruno Lobão, Galvão-Coelho, Nicole Leite, Arcoverde, Emerson, Araujo, Draulio B., Araujo, Draulio B |
| Abstract |
Ayahuasca, the vine of the souls in Quechua, is a psychedelic brew with a few formulations that most often include the bark of a liana in the Malpighiaceae family (Banisteriopsis caapi), with leaves from a shrub in the coffee family Rubiaceae (Psychotria viridis). Mixed with water and boiled for hours or days, it produces a brownish-colored liquid with a strong and characteristic taste. Ayahuasca contains the psychedelic tryptamine N,N-Dimethyltryptamine (DMT), and Monoamine Oxidase Inhibitors (MAOi), and in the past few years, it has been tested. In recent years its antidepressant properties have been put to the test. Evidence from open and randomized placebo-controlled clinical trials has shown encouraging results, indicating significant and rapid antidepressant effects, starting as early as 1 day after the ayahuasca intervention. In addition, we have explored the nature of these effects using multivariate measures. In this article, we will review the history, pharmacology, clinical trials, and clinical and behavioral markers associated with the antidepressant effects of ayahuasca. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 27% |
| Netherlands | 1 | 7% |
| Unknown | 10 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 87% |
| Practitioners (doctors, other healthcare professionals) | 1 | 7% |
| Scientists | 1 | 7% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 40 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 6 | 15% |
| Student > Ph. D. Student | 5 | 13% |
| Student > Doctoral Student | 2 | 5% |
| Student > Postgraduate | 2 | 5% |
| Researcher | 2 | 5% |
| Other | 1 | 3% |
| Unknown | 22 | 55% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 5 | 13% |
| Neuroscience | 4 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Medicine and Dentistry | 2 | 5% |
| Other | 2 | 5% |
| Unknown | 23 | 57% |