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Mendeley readers
| Chapter title |
Predicting RNA–RNA Interactions Using RNAstructure
|
|---|---|
| Chapter number | 4 |
| Book title |
RNA Structure Determination
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-6433-8_4 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6431-4, 978-1-4939-6433-8
|
| Authors |
Laura DiChiacchio, David H. Mathews |
| Abstract |
RNA-RNA binding is a required step for many regulatory and catalytic processes in the cell. Identifying RNA-RNA hybridization sites is challenging because of the competition between intramolecular and intermolecular structure formation. A complete picture of RNA-RNA binding includes an understanding of single-stranded folding and binding site accessibility, and is strongly concentration-dependent. This chapter provides guidance for using RNAstructure to predict RNA-RNA binding sites and RNA-RNA structures, utilizing free energy minimization and partition function calculations. RNAstructure is freely available at http://rna.urmc.rochester.edu/RNAstructure.html . |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 15 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 40% |
| Student > Bachelor | 2 | 13% |
| Student > Master | 2 | 13% |
| Researcher | 1 | 7% |
| Student > Postgraduate | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 3 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 27% |
| Agricultural and Biological Sciences | 4 | 27% |
| Medicine and Dentistry | 2 | 13% |
| Immunology and Microbiology | 1 | 7% |
| Chemistry | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 3 | 20% |