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Mendeley readers
| Chapter title |
Investigation of K(ATP) channel endocytosis and cell surface density by Biotinylation and Western blotting.
|
|---|---|
| Chapter number | 6 |
| Book title |
Potassium Channels
|
| Published in |
Methods in molecular biology, January 2008
|
| DOI | 10.1007/978-1-59745-526-8_6 |
| Pubmed ID | |
| Book ISBNs |
978-1-934115-65-7, 978-1-59745-526-8
|
| Authors |
Smith, Andrew J, Sivaprasadarao, Asipu, Smith, Andrew J., Andrew J. Smith, Asipu Sivaprasadarao |
| Abstract |
Macroscopic ion channel currents (I) are a product of the channel open probability (P(o)), the single channel current (i) and the number of channels present on the cell surface (N) at any given time (I = P(o)iN). Endocytosis has been shown to be one of the key determinants of cell surface channel density and defects of this process have been linked to diseases relating to ion channel dysfunction. Biotinylation allows the selective labelling and isolation of surface exposed proteins which can then be identified by Western blotting. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Professor > Associate Professor | 1 | 20% |
| Researcher | 1 | 20% |
| Other | 1 | 20% |
| Unknown | 2 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 40% |
| Nursing and Health Professions | 1 | 20% |
| Unknown | 2 | 40% |