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Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy

Overview of attention for book
Cover of 'Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy'

Table of Contents

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    Book Overview
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    Chapter 1 Molecular Cell Biology of Apoptosis and Necroptosis in Cancer.
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    Chapter 2 Clearance of Dying Cells by Phagocytes: Mechanisms and Implications for Disease Pathogenesis.
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    Chapter 3 Microenvironmental Effects of Cell Death in Malignant Disease.
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    Chapter 4 Apoptotic Caspases in Promoting Cancer: Implications from Their Roles in Development and Tissue Homeostasis.
  6. Altmetric Badge
    Chapter 5 Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
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    Chapter 6 Immunogenic Apoptotic Cell Death and Anticancer Immunity.
  8. Altmetric Badge
    Chapter 7 Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
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    Chapter 8 Novel Approaches to Apoptosis-Inducing Therapies.
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    Chapter 9 Killing Is Not Enough: How Apoptosis Hijacks Tumor-Associated Macrophages to Promote Cancer Progression.
Attention for Chapter 7: Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
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About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

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19 Mendeley
Summary X
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Chapter title
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
Chapter number 7
Book title
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
Published in
Advances in experimental medicine and biology, August 2016
DOI 10.1007/978-3-319-39406-0_7
Pubmed ID
27558821
Book ISBNs
978-3-31-939404-6, 978-3-31-939406-0
Authors

Frey, Benjamin, Derer, Anja, Scheithauer, Heike, Wunderlich, Roland, Fietkau, Rainer, Gaipl, Udo S, Benjamin Frey, Anja Derer, Heike Scheithauer, Roland Wunderlich, Rainer Fietkau, Udo S. Gaipl

Editors

Christopher D. Gregory

Abstract

Radiotherapy (RT) predominantly is aimed to induce DNA damage in tumour cells that results in reduction of their clonogenicity and finally in tumour cell death. Adaptation of RT with higher single doses has become necessary and led to a more detailed view on what kind of tumour cell death is induced and which immunological consequences result from it. RT is capable of rendering tumour cells immunogenic by modifying the tumour cell phenotype and the microenvironment. Danger signals are released as well as the senescence-associated secretory phenotype. This results in maturation of dendritic cells and priming of cytotoxic T cells as well as in activation of natural killer cells. However, RT on the other hand can also result in immune suppressive events including apoptosis induction and foster tumour cell proliferation. That's why RT is nowadays increasingly combined with selected immunotherapies.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 4 21%
Student > Ph. D. Student 4 21%
Student > Master 4 21%
Student > Bachelor 3 16%
Professor > Associate Professor 2 11%
Other 0 0%
Unknown 2 11%
Readers by discipline Count As %
Medicine and Dentistry 4 21%
Agricultural and Biological Sciences 3 16%
Pharmacology, Toxicology and Pharmaceutical Science 2 11%
Biochemistry, Genetics and Molecular Biology 2 11%
Immunology and Microbiology 2 11%
Other 1 5%
Unknown 5 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2016.
All research outputs
#13,877,324
of 23,923,788 outputs
Outputs from Advances in experimental medicine and biology
#1,896
of 5,073 outputs
Outputs of similar age
#182,087
of 344,397 outputs
Outputs of similar age from Advances in experimental medicine and biology
#25
of 81 outputs
Altmetric has tracked 23,923,788 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,073 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 344,397 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.

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