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Mouse Models for Drug Discovery

Overview of attention for book
Cover of 'Mouse Models for Drug Discovery'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Genetically Defined Strains in Drug Development and Toxicity Testing.
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    Chapter 2 Mouse Models for Drug Discovery
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    Chapter 3 Mouse Models for Drug Discovery
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    Chapter 4 Mouse Models for Drug Discovery
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    Chapter 5 Mouse Models for Drug Discovery
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    Chapter 6 Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.
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    Chapter 7 A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics.
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    Chapter 8 Mouse Models for Drug Discovery
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    Chapter 9 Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.
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    Chapter 10 Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery.
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    Chapter 11 Cholesterol Absorption and Metabolism.
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    Chapter 12 Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening.
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    Chapter 13 Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research.
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    Chapter 14 Murine Model for Colitis-Associated Cancer of the Colon.
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    Chapter 15 Mouse Models for Drug Discovery
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    Chapter 16 Mouse Models for Drug Discovery
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    Chapter 17 Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders.
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    Chapter 18 Mouse Models for Drug Discovery
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    Chapter 19 Mouse Models for Drug Discovery
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    Chapter 20 Mouse Models for Drug Discovery
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    Chapter 21 Mouse Models for Drug Discovery
Attention for Chapter 14: Murine Model for Colitis-Associated Cancer of the Colon.
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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1 X user
wikipedia
2 Wikipedia pages

Citations

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7 Dimensions

Readers on

mendeley
101 Mendeley
Summary X Wikipedia Dimensions citations
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Chapter title
Murine Model for Colitis-Associated Cancer of the Colon.
Chapter number 14
Book title
Mouse Models for Drug Discovery
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3661-8_14
Pubmed ID
27150094
Book ISBNs
978-1-4939-3659-5, 978-1-4939-3661-8
Authors

Ashley J. Snider, Agnieszka B. Bialkowska, Amr M. Ghaleb, Vincent W. Yang, Lina M. Obeid, Yusuf A. Hannun, Snider, Ashley J., Bialkowska, Agnieszka B., Ghaleb, Amr M., Yang, Vincent W., Obeid, Lina M., Hannun, Yusuf A.

Editors

Gabriele Proetzel, Michael V. Wiles

Abstract

Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), significantly increases the risk for development of colorectal cancer. Specifically, dysplasia and cancer associated with IBD (colitis-associated cancer or CAC) develop as a result of repeated cycles of injury and healing in the intestinal epithelium. Animal models are utilized to examine the mechanisms of CAC, the role of epithelial and immune cells in this process, as well as the development of novel therapeutic targets. These models typically begin with the administration of a carcinogenic compound, and inflammation is caused by repeated cycles of colitis-inducing agents. This review describes a common CAC model that utilizes the pro-carcinogenic compound azoxymethane (AOM) followed by dextran sulfate sodium (DSS) which induces the inflammatory insult.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 101 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 16%
Researcher 14 14%
Student > Bachelor 9 9%
Student > Master 9 9%
Student > Doctoral Student 6 6%
Other 9 9%
Unknown 38 38%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 25 25%
Agricultural and Biological Sciences 14 14%
Medicine and Dentistry 12 12%
Immunology and Microbiology 3 3%
Nursing and Health Professions 2 2%
Other 8 8%
Unknown 37 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2022.
All research outputs
#6,441,933
of 22,881,964 outputs
Outputs from Methods in molecular biology
#1,954
of 13,132 outputs
Outputs of similar age
#103,675
of 393,701 outputs
Outputs of similar age from Methods in molecular biology
#232
of 1,471 outputs
Altmetric has tracked 22,881,964 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 13,132 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,701 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.

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