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Mouse Models for Drug Discovery

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Cover of 'Mouse Models for Drug Discovery'

Table of Contents

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    Book Overview
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    Chapter 1 Genetically Defined Strains in Drug Development and Toxicity Testing.
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    Chapter 2 Mouse Models for Drug Discovery
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    Chapter 3 Mouse Models for Drug Discovery
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    Chapter 4 Mouse Models for Drug Discovery
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    Chapter 5 Mouse Models for Drug Discovery
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    Chapter 6 Human FcRn Transgenic Mice for Pharmacokinetic Evaluation of Therapeutic Antibodies.
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    Chapter 7 A Humanized Mouse Model to Study Human Albumin and Albumin Conjugates Pharmacokinetics.
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    Chapter 8 Mouse Models for Drug Discovery
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    Chapter 9 Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.
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    Chapter 10 Mouse Models of Type 2 Diabetes Mellitus in Drug Discovery.
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    Chapter 11 Cholesterol Absorption and Metabolism.
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    Chapter 12 Skin Diseases in Laboratory Mice: Approaches to Drug Target Identification and Efficacy Screening.
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    Chapter 13 Chronic Myeloid Leukemia (CML) Mouse Model in Translational Research.
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    Chapter 14 Murine Model for Colitis-Associated Cancer of the Colon.
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    Chapter 15 Mouse Models for Drug Discovery
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    Chapter 16 Mouse Models for Drug Discovery
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    Chapter 17 Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders.
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    Chapter 18 Mouse Models for Drug Discovery
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    Chapter 19 Mouse Models for Drug Discovery
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    Chapter 20 Mouse Models for Drug Discovery
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    Chapter 21 Mouse Models for Drug Discovery
Attention for Chapter 17: Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders.
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Chapter title
Repetitive Behavioral Assessments for Compound Screening in Mouse Models of Autism Spectrum Disorders.
Chapter number 17
Book title
Mouse Models for Drug Discovery
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3661-8_17
Pubmed ID
27150097
Book ISBNs
978-1-4939-3659-5, 978-1-4939-3661-8
Authors

Stacey J. Sukoff Rizzo Ph.D., Stacey J. Sukoff Rizzo

Editors

Gabriele Proetzel, Michael V. Wiles

Abstract

Treatments for repetitive behaviors in Autism Spectrum Disorders (ASD) and other neurodevelopmental disorders remain an unmet medical need. Mouse models are highly valuable tools for investigating the underlying pathophysiology, genetics, and neurocircuitry of ASD, and can also be characterized for ASD-related phenotypes including repetitive behaviors and stereotypies. This chapter describes methods that can be employed for the assessment of repetitive behavior phenotypes and the evaluation of the ability of test compounds to attenuate repetitive behaviors in mouse models of ASD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 30%
Researcher 2 20%
Student > Ph. D. Student 1 10%
Student > Doctoral Student 1 10%
Unknown 3 30%
Readers by discipline Count As %
Neuroscience 3 30%
Nursing and Health Professions 1 10%
Biochemistry, Genetics and Molecular Biology 1 10%
Medicine and Dentistry 1 10%
Social Sciences 1 10%
Other 0 0%
Unknown 3 30%

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