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Phase I Oncology Drug Development

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Cover of 'Phase I Oncology Drug Development'

Table of Contents

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    Book Overview
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    Chapter 1 The Development of a Drug: A Pharmaceutical Drug Development Perspective
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    Chapter 2 Paradigms in Cancer Drug Development: A Universe with Many Galaxies
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    Chapter 3 Preclinical Studies to Enable First in Human Clinical Trials
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    Chapter 4 Practicalities of Setting Up a Phase I Clinical Trial Unit Within an Academic Center
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    Chapter 5 Novel Trial Designs for Early Phase Clinical Trials
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    Chapter 6 Examining Performance of Phase I Designs: 3+3 Versus Bayesian Optimal Interval (BOIN)
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    Chapter 7 Considerations for the Attribution and Management of Toxicities in Phase I Clinical Trials
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    Chapter 8 Strategies for Incorporating Pharmacokinetic Studies into Oncology Phase I Trials
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    Chapter 9 Development of Pharmacodynamic Biomarkers for Phase I Trials
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    Chapter 10 Efficacy Considerations in Phase I Trials
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    Chapter 11 Considerations for the Development of Novel Chemotherapies and Antibody Drug Conjugates in Phase I Trials
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    Chapter 12 Development of Molecularly Targeted Agents in Early Phase Clinical Trials
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    Chapter 13 Incorporating Precision Medicine into Phase I Clinical Trials
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    Chapter 14 Incorporating Circulating Biomarkers into Clinical Trials
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    Chapter 15 Development of Immunotherapeutic Strategies for Early Phase Clinical Trials
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    Chapter 16 Radiotherapy Considerations and Strategic Approaches in Phase I Trials
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    Chapter 17 The Paradigm of Early Phase Studies in Hematological Malignancies
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    Chapter 18 Pharmacokinetic Considerations for Organ Dysfunction Clinical Trials in Early Drug Development
Attention for Chapter 17: The Paradigm of Early Phase Studies in Hematological Malignancies
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Chapter title
The Paradigm of Early Phase Studies in Hematological Malignancies
Chapter number 17
Book title
Phase I Oncology Drug Development
Published by
Springer, Cham, January 2020
DOI 10.1007/978-3-030-47682-3_17
Book ISBNs
978-3-03-047681-6, 978-3-03-047682-3
Authors

Vishwanath Sathyanarayanan, Swaminathan P. Iyer

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Mendeley readers

The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 1 100%
Readers by discipline Count As %
Unspecified 1 100%