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Histone Deacetylases: the Biology and Clinical Implication

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Cover of 'Histone Deacetylases: the Biology and Clinical Implication'

Table of Contents

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    Book Overview
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    Chapter 1 K-Acetylation and Its Enzymes: Overview and New Developments
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    Chapter 2 The Biology of HDAC in Cancer: The Nuclear and Epigenetic Components
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    Chapter 3 Deacetylation of Nonhistone Proteins by HDACs and the Implications in Cancer
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    Chapter 4 The Biology and Therapeutic Implications of HDACs in the Heart
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    Chapter 5 HDACs in skeletal muscle remodeling and neuromuscular disease.
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    Chapter 6 Rationale for HDAC Inhibitor Therapy in Autoimmunity and Transplantation
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    Chapter 7 The role of Mammalian sirtuins in the regulation of metabolism, aging, and longevity.
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    Chapter 8 Mitochondrial Sirtuins in the Regulation of Mitochondrial Activity and Metabolic Adaptation
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    Chapter 9 Characterization of Nuclear Sirtuins: Molecular Mechanisms and Physiological Relevance
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    Chapter 10 Structural Biology of Human Metal-Dependent Histone Deacetylases
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    Chapter 11 Sirtuin modulators.
Attention for Chapter 9: Characterization of Nuclear Sirtuins: Molecular Mechanisms and Physiological Relevance
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