| Chapter title |
Aspergillus Biofilms in Human Disease
|
|---|---|
| Chapter number | 4 |
| Book title |
Fungal Biofilms and related infections
|
| Published in |
Advances in experimental medicine and biology, June 2016
|
| DOI | 10.1007/5584_2016_4 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-942359-3, 978-3-31-942360-9
|
| Authors |
Williams, Craig, Rajendran, Ranjith, Ramage, Gordon, Craig Williams, Ranjith Rajendran, Gordon Ramage |
| Abstract |
The biofilm phenotype of Aspergillus species is an important and accepted clinical entity. While industrially these biofilms have been used extensively in important biofermentations, their role in clinical infection is less well defined. A recent flurry of activity has demonstrated that these interesting filamentous moulds have the capacity to form biofilms both in vitro and in vivo, and through various investigations have shown that these are exquisitely resistant to antifungal therapies through a range of adaptive resistance mechanisms independent of defined genetic changes. This review will explore the clinical importance of these biofilms and provide contemporary information with respect to their clinical management. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 26 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 15% |
| Student > Bachelor | 4 | 15% |
| Student > Master | 3 | 12% |
| Unspecified | 3 | 12% |
| Student > Ph. D. Student | 2 | 8% |
| Other | 3 | 12% |
| Unknown | 7 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 19% |
| Unspecified | 4 | 15% |
| Immunology and Microbiology | 4 | 15% |
| Biochemistry, Genetics and Molecular Biology | 2 | 8% |
| Nursing and Health Professions | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 9 | 35% |